Results 91 to 100 of about 452,650 (302)

Update on the activity of delafloxacin against acute bacterial skin and skin-structure infection isolates from European hospitals (2014–2019)

open access: yesJournal of Global Antimicrobial Resistance, 2020
Objectives: Delafloxacin is a broad-spectrum anionic fluoroquinolone with activity against Gram-positive and Gram-negative organisms, including methicillin-resistant Staphylococcus aureus.
Dee Shortridge   +3 more
doaj   +1 more source

Skin and skin structure infections: treatment with newer generation fluoroquinolones

open access: yesTherapeutics and Clinical Risk Management, 2007
Skin and skin structure infections (SSSI) are an emerging issue in healthcare. They are responsible for increasing heathcare utilization, both in hospitalizations and intravenous antibiotic use. SSSI are caused by an evolving variety of pathogens, including Gram-positive, Gram-negative, and anaerobic bacteria.
Philip, Giordano   +3 more
openaire   +3 more sources

Super Staph in the Community: Is It Evolving? [PDF]

open access: yes, 2015
Staphylococcus aureus infections are a common cause of disease, particularly in colonized people. They frequently cause staph infections and are often dubbed “Super Staph” because they are virulent and multidrug resistant. Recently, a series of published
Gillen, Alan L., Walters, Rachel
core   +1 more source

Borrelia burgdorferi Manipulates Innate and Adaptive Immunity to Establish Persistence in Rodent Reservoir Hosts. [PDF]

open access: yes, 2017
Borrelia burgdorferi sensu lato species complex is capable of establishing persistent infections in a wide variety of species, particularly rodents. Infection is asymptomatic or mild in most reservoir host species, indicating successful co-evolution of ...
Baumgarth, Nicole, Tracy, Karen E
core   +1 more source

An Engineered Living Material With Pro‐Angiogenic Activity Inducible by Near‐Infrared Light

open access: yesAdvanced Functional Materials, EarlyView.
NIR‐responsive engineered living materials (ELMs) for controlled angiogenesis: Near‐infrared (800 nm) light activates engineered probiotic bacteria within alginate‐based living materials to secrete a blood vessel‐regenerating protein. The released protein promotes pro‐angiogenic effects in endothelial networks and chick chorioallantoic membranes.
Anwesha Chatterjee   +4 more
wiley   +1 more source

History-dependent switch-like differentiation of keratinocytes in response to skin barrier damage.

open access: yesPLoS Computational Biology
The epidermis is formed by layers of keratinocytes with increasing levels of differentiation towards the outer skin called skin barrier, which protects our body from environmental stressors and dehydration.
Elisa Domíguez-Hüttinger   +5 more
doaj   +1 more source

Photo‐Controlled Antibacterial Drug Release From DASA‐Coated Silica Particles for Improved Treatment of Wound Infections

open access: yesAdvanced Functional Materials, EarlyView.
Synthesis and characterization of light‐responsive donor–acceptor Stenhouse adducts (DASA)‐coated chlorhexidine‐loaded silica nanoparticles. Such a controllable drug‐delivery system enables the release of the antimicrobial drug on demand and in consecutive cycles, thereby maintaining the concentration within the therapeutic window.
Michèle Clerc   +9 more
wiley   +1 more source

Current Status of Defensins and Their Role in Innate and Adaptive Immunity [PDF]

open access: yes, 2002
Naturally occurring antimicrobial cationic polypeptides play a major role in innate and adaptive immunity. These polypeptides are found to be either linear and unstructured or structured through disulfide bonds.
Dentino, Andrew R., Raj, Periathamby A.
core   +1 more source

Regulated Ion‐Diffusion Hydrogels for Subtle and Multimodal Temperature‐Strain Sensing in Wound Monitoring

open access: yesAdvanced Functional Materials, EarlyView.
A soft, dual‐channel hydrogel patch enables simultaneous detection of wound temperature and strain by integrating ion‐diffusion‐mediated thermoelectric and resistive sensing. The conformal design maintains stable performance during motion, capturing subtle inflammatory and mechanical changes for continuous wound monitoring.
Yu Fang   +7 more
wiley   +1 more source

Panamanian frog species host unique skin bacterial communities

open access: yesFrontiers in Microbiology, 2015
Vertebrates, including amphibians, host diverse symbiotic microbes that contribute to host disease resistance. Globally, and especially in montane tropical systems, many amphibian species are threatened by a chytrid fungus, Batrachochytrium dendrobatidis
Lisa K. Belden   +14 more
doaj   +1 more source

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