Results 261 to 270 of about 452,650 (302)

Loracarbef vs. cefaclor in pediatric skin and skin structure infections

The Pediatric Infectious Disease Journal, 1992
A double blind, randomized clinical trial involving 214 children, ages 6 months to 12 years, compared the safety and effectiveness of the new carbacephem loracarbef and the cephalosporin cefaclor for the treatment of skin and skin structure infections. The two agents were given primarily as oral suspensions.
M J, Hanfling, S A, Hausinger, J, Squires   +2 more
openaire   +2 more sources

Dirithromycin in the treatment of skin and skin structure infections

Journal of Antimicrobial Chemotherapy, 1993
The efficacy and safety of dirithromycin were compared with those of erythromycin or miocamycin for the treatment of skin and/or skin structure infections in two double-blind, double-dummy, randomized, parallel group, multicentre studies conducted in North America and in Europe, and one single-blind, randomized, parallel group study conducted in Italy.
M, Derriennic, J P, Escande
openaire   +2 more sources

Ceftobiprole medocaril for skin and skin-structure infections

Expert Opinion on Drug Metabolism & Toxicology
On 3 April 2024, the United States Food and Drug Administration (FDA) approved ceftobiprole medocaril sodium (Zevtera) for injection for the treatment of adults with acute bacterial skin and skin structure infections (ABSSSI) as well as patients with Staphylococcus aureus bloodstream infections and patients 3 months to less than 18 years old with ...
openaire   +2 more sources

The evaluation and treatment of complicated skin and skin structure infections

Expert Opinion on Pharmacotherapy, 2008
Skin and skin structure infections are frequently encountered in clinical practice. Fortunately, these infections usually produce only mild to moderate symptoms and signs. Some, however, are severe and may even be life-threatening.To review the approach to the evaluation and treatment of patients with complicated skin and skin structure infections and ...
Paul B, Cornia, Heather L, Davidson, Benjamin A, Lipsky   +2 more
openaire   +2 more sources

Current and future management of serious skin and skin-structure infections

The American Journal of Medicine, 1996
The purpose of this study was to compare in a randomized, open-label clinical study, the efficacy and safety of cefepime (1 g every 12 hours) with that of ceftazidime (1 g every 8 hours) in patients with serious skin and skin-structure infections. Of 298 patients enrolled in the study, 130 with serious skin and skin-structure infections were evaluable.
R, Schwartz, L R, Das-Young, C, Ramirez-Ronda, E, Frank   +3 more
openaire   +2 more sources

Complicated Skin and Skin Structure Infection After Erysipelas

The International Journal of Lower Extremity Wounds, 2016
Erysipelas are common soft tissue infections responding to first-line antibiosis. Because of factors of related to responsible bacteria and host, complications can occur that need extensive surgery in addition to intensified drug therapy. We report on a 65-year-old woman with leg ulcer who developed an absceding and necrotizing panniculitis of the ...
Uwe, Wollina, Dana, Langner, Birgit, Heinig, Jacqueline, Schönlebe, Andreas, Nowak   +4 more
openaire   +2 more sources

Resistant pathogen-associated skin and skin-structure infections: antibiotic options

Expert Review of Anti-infective Therapy, 2010
Complicated skin and skin-structure infections (cSSSIs) are among the most common infections treated in the hospital setting. They are a significant clinical problem, partially owing to increasing resistance of infecting bacteria to current antibiotic therapies (nosocomial and community-acquired methicillin-resistant Staphylococcus aureus, extended ...
openaire   +2 more sources

Current issues in uncomplicated skin and skin structure infections

Expert Review of Dermatology, 2007
Superficial skin infections caused by Staphylococcus aureus and Streptococcus pyogenes include primary infections, such as impetigo, and secondary infections, such as secondarily infected dermatitis or traumatic lesions. Such infections are some of the most common indications for antimicrobial therapy, with the particular choice of therapy depending on
Moise L Levy, Jeffrey M Weinberg
openaire   +1 more source

The Role of Fluoroquinolones in Skin and Skin Structure Infections

American Journal of Clinical Dermatology, 2002
Skin and skin structure infections encompass a broad range of clinical presentations and disease severity. Antimicrobial therapy is clearly beneficial for both recovery from these infections as well as preventing disease progression. Fluoroquinolones are potent broad spectrum antimicrobial agents with the older agents characterized as having broad ...
openaire   +2 more sources

Bacterial Infections of the Skin and Skin Structures

2019
Skin and skin structure infections caused by bacteria involve the skin layers and underlying connective tissue. Cellulitis and abscess are two of the most common manifestations of these types of infections. Streptococcus pyogenes (group A streptococcus) is the predominant cause of cellulitis, but Staphylococcus aureus should also be considered.
openaire   +1 more source