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The Role of the Skin Barrier in Occupational Skin Diseases

2016
Occupational skin diseases (OSDs) are the second most common occupational diseases worldwide. Occupational contact dermatitis (OCD) is the most frequent OSD, and comprises irritant contact dermatitis (ICD), allergic contact dermatitis (ACD), contact urticaria and protein contact dermatitis.
Pranee, Kasemsarn   +2 more
openaire   +2 more sources

The skin's barrier.

Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 2010
The skin provides an effective barrier between the organism and the environment, preventing the invasion of pathogens and fending off chemical and physical assaults, as well as the unregulated loss of water and solutes. In this review we provide an overview of several components of the physical barrier, as well as how barrier function is regulated and ...
J M, Jensen, E, Proksch
openaire   +1 more source

The barrier beyond the skin

Italian Journal of Dermatology and Venereology, 2021
Moliterni E   +4 more
openaire   +3 more sources

Penetration through the Skin Barrier

2016
The skin is a strong and flexible organ with barrier properties essential for maintaining homeostasis and thereby human life. Characterizing this barrier is the ability to prevent some chemicals from crossing the barrier while allowing others, including medicinal products, to pass at varying rates.
Nielsen, Jesper Bo   +2 more
openaire   +3 more sources

Computational Modeling of the Skin Barrier

2011
A simulation environment for the numerical calculation of permeation processes through human skin has been developed. In geometry models that represent the actual cell morphology of stratum corneum (SC) and deeper skin layers, the diffusive transport is simulated by a finite volume method. As reference elements for the corneocyte cells and lipid matrix,
Arne, Naegel   +2 more
openaire   +2 more sources

Filaggrin and Skin Barrier Function

2016
The skin barrier function is greatly dependent on the structure and composition of the uppermost layer of the epidermis, the stratum corneum (SC), which is made up of flattened anucleated cells surrounded by highly organized and continuous lipid matrix.
Kezic, Sanja, Jakasa, Ivone
openaire   +3 more sources

Modulation of the Barrier Function of the Skin

Skin Pharmacology and Physiology, 2001
Transport of xenobiotics across the stratum corneum, the rate-controlling membrane of skin, is slow and the mechanism appears complex. However, the basic transfer is controlled by fundamental physicochemical concepts, the predominant of which are partition (K), diffusion (D) and solubility (C<sub>s</sub>).
openaire   +2 more sources

The skin barrier: An extraordinary interface with an exceptional lipid organization

Progress in Lipid Research, 2023
Joke A Bouwstra   +2 more
exaly  

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