Results 91 to 100 of about 8,316,961 (358)

Psoriasis today: experiences of healthcare and impact on quality of life in a major UK cohort [PDF]

open access: yes, 2015
Aim: To establish how people with psoriasis in the United Kingdom today experience living with their condition including diagnosis, treatment, healthcare provision and impact on daily life.
Gilbert, Annie   +4 more
core   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Comparison of differences in knowledge about skin care bettwen young women and man

open access: yesJournal of Education, Health and Sport, 2017
Introduction: The skin of modern people is exposed daily to a number of irritants like stress, consequences of inadequate diet, exposure to chemicals and plastics.
Katarzyna Bojarczuk   +4 more
doaj   +1 more source

Hemp (Cannabis sativa L.) as a Resource for Green Cosmetics: Yield of Seeds and Fatty Acids Composition of 20 Varieties under the Growing Conditions of Organic Farming in Austria [PDF]

open access: yes, 2004
The interest in hemp (non-drug Cannabis sativa L.) for skin care and cosmetic use is due to the high content of oil, especially unsaturated fatty acids in seed with technological and therapeutic effects.
Kobert, J.   +4 more
core  

Skin Cancers Among Albinos at a University Teaching Hospital in Northwestern Tanzania: A Retrospective Review of 64 Cases. [PDF]

open access: yes, 2012
Skin cancers are a major risk associated with albinism and are thought to be a major cause of death in African albinos. The challenges associated with the care of these patients are numerous and need to be addressed.
A Yakubu   +33 more
core   +3 more sources

Beneficial effects of food supplements based on hydrolyzed collagen for skin care (Review)

open access: yesExperimental and Therapeutic Medicine, 2019
Ageing is a complex, multi-step process which involves, among others loss of collagen and elastin. Collagen is found in large amounts in the body, especially in the dermis layer.
M. Lupu   +4 more
semanticscholar   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Scope of Nanotechnology in Cosmetics: Dermatology and Skin Care Products

open access: yesJournal of Medicinal and Chemical Sciences, 2019
Women and men have been wearing cosmetics for centuries, although the styles have certainly undergone some dramatic changes over time. Cosmetics is a very vast field which has served humanity throughout the course of history.In old age, it was believed ...
Awais Hameed   +4 more
semanticscholar   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

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