Results 81 to 90 of about 3,544,346 (338)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Sistem Pendeteksian Keserasian Warna Kulit dan Busana Secara Otomatis Untuk Jenis Kelamin Perempuan Berbasis Image Processing

Jurnal Nasional Teknik Elektro, 2014
Compatibility of the clothes become a necessity that can not be avoided by everyone, because accuracy in choosing the color of the clothes will be very supportive of woman's appearance.
Meza Silvana, Rahmadi Kurnia
doaj  

High-density genetic map and quantitative trait loci map of skin color in hawthorn (Crataegus pinnatifida bge. Var. major N.E.Br.)

Frontiers in Genetics
Fruit skin color is an important trait of the hawthorn tree, which has an important influence on fruit quality. Crataegus pinnatifida Bge. var. Major N.E.Br. Is one of the most widely cultivated varieties in China and has a long history of medicinal use.
Dongsheng Wang, Beibei Cheng, Beibei Cheng, Beibei Cheng, Jijun Zhang, Jijun Zhang, Jijun Zhang   +6 more
doaj   +1 more source

Do masculine men smell better? An association between skin color masculinity and female preferences for body odor [PDF]

, 2017
This work was supported by Fundação para a Ciência e a Tecnologia and Programa Operacional de Potencial Humano/Fundo Social Europeu (SFRH/BD/77592/2011 to M.L.C.).A recent study claimed face skin color as a sexually dimorphic variable that influences ...
Alho, Laura, Bem-Haja, Pedro, Carrito, Mariana L., Ferreira, Jacqueline, Perrett, David I., Santos, Isabel M., Silva, Carlos F., Soares, Sandra C.   +7 more
core   +2 more sources

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

A study on clinical spectrum of pigmentary alterations among the pediatric population

Indian Journal of Paediatric Dermatology, 2020
Background: Human skin color is the result of a complex interplay of various intrinsic and extrinsic factors and has great heterogeneity across the globe.
Sameer Abrol, Rohini Sharma
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

SWATH-MS-facilitated proteomic profiling of fruit skin between Fuji apple and a red skin bud sport mutant

BMC Plant Biology, 2019
Background Apple is one of the most popular fruit crops world-wide and its skin color is an important quality consideration essential for commercial value.
Mo-Xian Chen, Chao Sun, Kai-Lu Zhang, Yu-Chen Song, Yuan Tian, Xi Chen, Ying-Gao Liu, Neng-Hui Ye, Jianhua Zhang, Shenchun Qu, Fu-Yuan Zhu   +10 more
doaj   +1 more source

Shared Genetic Effects and Antagonistic Pleiotropy Between Multiple Sclerosis and Common Cancers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epidemiologic studies have reported inconsistent altered cancer risk in individuals with multiple sclerosis (MS). Factors such as immune dysregulation, comorbidities, and disease‐modifying therapies may contribute to this variability.
Asli Buyukkurt, Marius Ygonia, Ali Manouchehrinia, Philippe Lefrançois, Ingrid Kockum, Adil Harroud   +5 more
wiley   +1 more source