Results 31 to 40 of about 1,627,653 (237)

Alopecia areata: a multifactorial autoimmune condition [PDF]

, 2019
Alopecia areata is an autoimmune disease that results in non-scarring hair loss, and it is clinically characterised by small patches of baldness on the scalp and/or around the body. It can later progress to total loss of scalp hair (Alopecia totalis) and/
Butcher, John P., Henriquez, Fiona L., Reid, Stuart, Simakou, Teontor   +3 more
core   +1 more source

Dermatoscopic aspects of the Microphthalmia with Linear Skin Defects (MLS) Syndrome [PDF]

Anais Brasileiros de Dermatologia, 2014
The association of microphthalmia and linear skin defects was named microphthalmia with linear skin defects syndrome (MLS) or MIDAS syndrome (microphthalmia, dermal aplasia, and sclerocornea), an X-chromosomal disorder manifesting mainly in females.
Hiram Larangeira de Almeida Jr., Gabriela Rossi, Luciana Boff de Abreu, Cristina Bergamaschi, Alessandra Banaszeski da Silva, Kerstin Kutsche   +5 more
doaj   +1 more source

Making the invisible visible [PDF]

, 2016
In this review, I will discuss how careful scrutiny of genetic skin disorders could help us to understand human biology. Like other organs, the skin and its appendages, such as hairs and teeth, experience fundamental biological processes ranging from ...
Ando, Attié, Badolato, Barnett, Basmanav, Betz, Bin, Boissy, Bondurand, Bultema, Byers, Clark, Courcet, Cui, Cullinane, Cullinane, Dauphinee, Dell’Angelica, Di Pietro, Edery, Fischer, Gerondopoulos, Giebel, Giebel, Helip-Wooley, Hume, Hume, Iqbal, Ji, Kono, Kumano, Lee, Li, Lugassy, Lugassy, Luzio, Maurice A.M. van Steensel, McGlinchey, Miyamura, Murphy, Ménasché, Ménasché, Nagle, Newton, Olivares, Pastural, Pingault, Planko, Potterf, Puri, Qiu, Sato-Jin, Sckolnick, Sepulveda, Setty, Singh, Sitaram, Sánchez-Martín, Tassabehji, Tassabehji, Theos, Uttam, Vachtenheim, Van Raamsdonk, Van Steensel, Van Steensel, Weber, Wei, Wilson, Winder, Wu, Yamaguchi, Zazo Seco, Zhang, Zucca   +74 more
core   +2 more sources

Inflammasomes in Common Immune-Related Skin Diseases

Frontiers in Immunology, 2020
The inflammasome is an important protein complex that cleaves the proinflammatory cytokines pro-IL-1β and pro-IL-18 into their active forms. Owing to its critical role in eliciting innate immune responses, IL-1β has been suggested to contribute to ...
L. Tang, F. Zhou
semanticscholar   +1 more source

Vohwinkel syndrome: ichthyosiform variant in a family [PDF]

Anais Brasileiros de Dermatologia, 2018
: Vohwinkel syndrome belongs to the group of hereditary palmoplantar keratoderma, having an autosomal dominant inheritance. In this report, the authors present a case of a four-year-old boy with diffuse scaling over his entire body and transgredient ...
Clarissa Prieto Herman Reinehr, Juliano Peruzzo, Tania Cestari   +2 more
doaj   +1 more source

Vitiligo and autoimmune thyroid disorders [PDF]

, 2017
Vitiligo represents the most common cause of acquired skin, hair and oral depigmentation, affecting 0.5-1% of the population worldwide. It is clinically characterized by the appearance of disfiguring circumscribed skin macules following melanocyte ...
Baldini, Enke, Carbotta, Giovanni, Catania, Antonio, D'Armiento, Eleonora, Odorisio, Teresa, Persechino, Severino, Pironi, Daniele, Rendina, Roberta, Sorrenti, Salvatore, Tartaglia, Francesco, Ulisse, Salvatore   +10 more
core   +2 more sources

Myeloperoxidase Modulates Inflammation in Generalized Pustular Psoriasis and Additional Rare Pustular Skin Diseases

American Journal of Human Genetics, 2020
Generalized pustular psoriasis (GPP) is a severe multi-systemic inflammatory disease characterized by neutrophilic pustulosis and triggered by pro-inflammatory IL-36 cytokines in skin.
S. Haskamp, H. Bruns, M. Hahn, M. Hoffmann, A. Gregor, Sabine Löhr, J. Hahn, C. Schauer, Mark Ringer, C. Flamann, B. Frey, A. Lesner, C. Thiel, A. Ekici, S. von Hörsten, G. Assmann, C. Riepe, Maximilien Euler, K. Schäkel, S. Philipp, J. Prinz, R. Mössner, Florina Kersting, M. Sticherling, A. Sefiani, J. Lyahyai, W. Sondermann, V. Oji, P. Schulz, D. Wilsmann-Theis, H. Sticht, G. Schett, A. Reis, S. Uebe, S. Frey, U. Hüffmeier   +35 more
semanticscholar   +1 more source

Development of Onchocerca volvulus in humanized NSG mice and detection of parasite biomarkers in urine and serum. [PDF]

, 2018
BACKGROUND: The study of Onchocerca volvulus has been limited by its host range, with only humans and non-human primates shown to be susceptible to the full life cycle infection.
Abraham, David, Bennuru, Sasisekhar, Eberhard, Mark L., Hess Ligas, Jessica A., Lustigman, Sara, Nutman, Thomas B., Patton, John B., Torigian, April R.   +7 more
core   +3 more sources

Epigenetic factors involved in the pathophysiology of inflammatory skin diseases.

Journal of Allergy and Clinical Immunology, 2020
Epigenetics has been discussed as a potential factor influencing the pathophysiology and severity of inflammatory skin diseases. In recent years, emerging evidence suggests that epigenetic mechanisms are involved in the pathophysiology of not only atopic
L. Möbus, S. Weidinger, H. Emmert
semanticscholar   +1 more source

Update on DNA methylation in UV radiation-related skin diseases

Pifu-xingbing zhenliaoxue zazhi, 2023
DNA methylation is a common epigenetic phenomenon that changes genetic expression without altering the DNA sequence. With deepening research on DNA methylation, more and more variable positions of methylation have been identified in a variety of diseases(
Wenting CHEN, Xinni ZHONG, Wei LI
doaj   +1 more source