The role of the host—Neutrophil biology
Periodontology 2000, EarlyView., 2023 Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
Parasites and allergies: a complex bidirectional relationship from evolutionary origins to modern therapeutics. [PDF]
Antonie Van LeeuwenhoekPacki K +9 more
europepmc +1 more source
Beyond the specimen: rethinking ornithological collecting in a changing world
Ibis, EarlyView.Natural history collections underpin a wide range of ornithological research, yet the context in which they operate is rapidly changing. Advances in genomics, digitization and analytical approaches are transforming what can be learned from specimens, while accelerating environmental change is increasing the need for temporally explicit, integrative ...
Ken Norris, Heather Avrili
wiley +1 more source
Life-Stage and Parasite-Induced Shifts in the Skin Mucus Proteome of Nile tilapia (<i>Oreochromis niloticus</i>). [PDF]
Biology (Basel)Yan N +9 more
europepmc +1 more source
Dual Host–Pathogen Screening of the Lung During Severe Influenza Using Spatial Transcriptomics
Immunology &Cell Biology, EarlyView.We performed genome‐wide spatial transcriptomics at 10 μm resolution on the lungs of mice infected with influenza A virus. We utilised publicly available scRNAseq reference datasets to identify cell types present. We found viral transcripts across all detected cell types, suggesting localised indiscriminate infection.
Marcus Z. W. Tong +9 more
wiley +1 more source
STAG Priming Preserves Paneth Cells and Limits Parasite‐Triggered Ileitis
Immunology &Cell Biology, EarlyView.Preservation of Paneth cells is associated with resistance to ileitis caused by Toxoplasma gondii. ABSTRACT Toxoplasma gondii triggered ileitis is a commonly used model for diseases affecting the small intestine, such as Crohn's Disease. Inflammation is primarily dependent on Th1‐mediated killing of Paneth cells, which consequently promotes intestinal ...
Ester Cristina Borges Araujo +8 more
wiley +1 more source
Living within: endosymbiosis in parasites of medical importance-profits, expenses, and implications for host-parasite interactions. [PDF]
Front Cell Infect MicrobiolAbdel Shafi IR +2 more
europepmc +1 more source
Tissue Resident Memory Cells: Friend or Foe?
Immunology, EarlyView.Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude +2 more
wiley +1 more source
Glass eels and viruses – a lesson learnt from stocking the eastern German Baltic Sea coast
Transboundary and Emerging Diseases, Accepted Article., 2022 Abstract Concerns about Anguillid herpesvirus 1 (AngHV‐1) in European eels, especially due to stocking measures, is increasingly coming into focus and raises questions regarding disease monitoring and prevention. In the past, stocking of AngHV‐1‐positive eels into waters assumed AngHV‐1‐free has led to a rapid increase of infected eels in the wild. For
Laura Kullmann +3 more
wiley +1 more source
Equitable access to monoclonal antibodies targeting parasites. [PDF]
Trends ParasitolThahir S +6 more
europepmc +1 more source