Results 41 to 50 of about 1,081,673 (217)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Applied Sciences, 2020 The need of a wide operating range and a high power density in electric machines for full- and hybrid electric vehicles in traction applications has led to an increase in the operating frequency of the machine.
Claudio Bianchini +5 more
doaj +1 more source
One Hundred and Fifty Years of Skin Effect
Applied Sciences, 2023 In 1873, J.C. Maxwell derived relations for current density and current in a solitary long cylindrical conductor supplied with variable current. According to Maxwell, the current density in a conductor increases towards the conductor surface.
Oldřich Coufal
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Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
Analysis for magnetic field disturbance of hybrid DC circuit breaker during breaking
High Voltage, 2022 The high current of hybrid DC circuit breaker (HCB) in the process of breaking generates strong transient magnetic field (MF), which may interfere with the normal operation of driver control units (DCUs).
Sihang Wu +7 more
doaj +1 more source
Identification of Fractional Models of an Induction Motor with Errors in Variables
Fractal and Fractional, 2023 The skin effect in modeling an induction motor can be described by fractional differential equations. The existing methods for identifying the parameters of an induction motor with a rotor skin effect suggest the presence of errors only in the output ...
Dmitriy Ivanov
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FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source