Results 161 to 170 of about 3,255,281 (310)

Biosynthesis of ecofriendly antibacterial nanoparticles with healing effects in a murine diabetic skin infection model. [PDF]

Sci Rep
Mustafa EA, Nada HG, Eraqi WA, Shamma RN, Elhifnawi HN, Abdeltawab NF.   +5 more
europepmc   +1 more source

Phosphorylated STYK1 Promotes Gemcitabine Resistance via Autophagy‐Mediated Cancer Stemness in Pancreatic Cancer

Advanced Science, EarlyView.
Gemcitabine resistance remains a major challenge in pancreatic ductal adenocarcinoma. This study identifies STYK1 as a key mediator of chemoresistance through autophagy‐dependent maintenance of cancer stemness. Gemcitabine‐activated AMPK phosphorylates STYK1 at Ser91 and Ser304, enhancing autophagy and stemness.
Xueying Dong, Shi Li, Chensong Huang, Xuehong Qian, Jieyu Guo, Yahao Guo, Guifang Wu, Qi Zhang, Hongfei Tan, Yu Han, Rui Zhang, Hao Lyu, Shuai Xiao, Dong Guo, Chaojun Yan, Wenying Qin, Changchun Li, Xing‐Zhen Chen, Ying Zhao, Cefan Zhou, Jingfeng Tang   +20 more
wiley   +1 more source

Liver–Skin Microphysiological System for Evaluating Topical Drug Delivery-Induced Liver Injury

ACS Omega
Kun Du, Bei Wang, Ning Yang, Jian Jin, Wei Liu, Feifei Pu, Lili Zou, Zilu Qu, Liuqing Chen   +8 more
doaj   +1 more source

Host Proteome Remodeling During Group A Streptococcus Skin Infection. [PDF]

Mol Cell Proteomics
Sanchez C, Wierzbicki IH, Bayne CF, Castaneda JC, Raygoza JM, Gonzalez DJ.   +5 more
europepmc   +1 more source

Targeted Restoration of the Microbial Tryptophan Oxidative Pathway Ameliorates Autism‐Like Behavioral and Synaptic Deficits

Advanced Science, EarlyView.
ABSTRACT Autism Spectrum Disorder (ASD) is associated with gut microbiota dysbiosis, yet the contribution of specific microbial metabolic pathways remains unclear. Reanalysis of a public ASD cohort revealed reduced functional potential in microbial tryptophan oxidative metabolism.
Rui Guo, Caian He, Xiao Xiao, Jingmeng Li, Zilong Zhang, Ying He, Chuanchuan Wang, Jiale Zhao, Jun Gong, Jiarui Liang, Tian Yuan, Haiting Sun, Xuebo Liu, Chao Gao, Zhigang Liu   +14 more
wiley   +1 more source

Detection of Nontuberculous Mycobacterial Skin Infection by Next-Generation Sequencing: A Pilot Study. [PDF]

J Clin Med
Liu JW, Ma X, Qian YT, Wang JW, Zhu CY, Ma DL.   +5 more
europepmc   +1 more source

Highly Flexible and Conformable ZnO/FeGa Magnetoelectric Heterostructures for Skin wound Healing

Advanced Science, EarlyView.
The magnetic field‐induced electric field generated by a highly flexile ZnO(piezoelectric)/FeGa(magnetostrictive) magnetoelectric heterostructure embedded in the low Young's modulus elastomer PDMS has been used to stimulate the wound healing processes.
Filippos Perdikos, Laia Bagur, Cristina Vaca, Aritz Lafuente, Joaquin Llacer‐Wintle, Bojan Ambrožič, Christina Stefani, Minsoo Kim, Goran Dražić, Darja Lisjak, Jordi Sort, Xiang‐Zhong Chen, Maria Jose Esplandiu, Salvador Pané, Carme Nogués, Josep Nogués, Andreu Blanquer, Borja Sepúlveda   +17 more
wiley   +1 more source

Fibroblast-derived CCL2 orchestrates immune responses and defends against Staphylococcus aureus skin infection. [PDF]

Cell Mol Immunol
Dokoshi T, Palomo-Irigoyen M, Dai K, Hashimoto T, Konishi H, Hivert L, Bagood M, Chan H, Almoughrabie S, Nakamura Y, Cavagnero KJ, Nakatsuji T, Fujiya M, Gallo RL.   +13 more
europepmc   +1 more source

Biofilm‐Binding Phages Enhance Biofilm Eradication by Synergistic Photothermal and Photodynamic Therapy

Advanced Science, EarlyView.
Engineered phage‐based trifunctional nanofibers are developed for synergistic biofilm eradication. Biofilm‐binding phages, armed with AuNPs and TCPP, serve as both warheads and scaffolds, endowing the phototherapy agents with biofilm‐anchoring ability. Upon light irradiation, AuNPs induce photothermal therapy, while TCPP generates 1O2 for photodynamic ...
Ying Cao, Tao Yang, Rui Wang, Hui‐Da Li, Xiao‐Yu Zhang, Feng Cheng, Ying Liu, Jian‐Hua Wang, Ting Yang, Chuanbin Mao   +9 more
wiley   +1 more source

ClpX-dependent regulatory pathway exacerbates <i>Streptococcus pyogenes</i> pathogenesis in diabetic skin infection. [PDF]

mBio
Liu S, Rosen AL, Olson BS, Lu Y, Hickerson S, Kau AL, Hultgren SJ, Caparon MG, Xu W.   +8 more
europepmc   +1 more source