Catechol Derivative‐Based Bioadhesives: Molecular Design for Precision Medical Adhesion
This study utilizes tree‐inspired side‐chain engineering to graft five catechol derivatives onto PVA, systematically revealing how side‐chain length and substituents regulate adhesion and cohesion properties. Among them, the PVA‐CA patch demonstrates superior tissue adhesion, biocompatibility, and promotes regeneration, establishing a programmable ...
Xueyu Wang +8 more
wiley +1 more source
Investigating interbrain synchrony under teamwork disruption: an fNIRS hyperscanning study. [PDF]
Réveillé C +7 more
europepmc +1 more source
TRIM40 Drives Pathological Cardiac Hypertrophy and Heart Failure via Ubiquitination of PKN2
This study identifies the E3 ligase TRIM40 as a key driver of pathological cardiac hypertrophy. TRIM40 binds PKN2 via its B‐box domain and, through its C29‐dependent catalytic activity, mediates K63‐linked ubiquitination of PKN2. This modification enhances PKN2 phosphorylation at Ser815, thereby driving hypertrophy.
Risheng Zhao +12 more
wiley +1 more source
A comprehensive model for characterizing Chinese female facial skin laxity by expert assessment, consumer perception, and noninvasive skin physiological parameters. [PDF]
Zi Y +6 more
europepmc +1 more source
“More” Artificial mRNAs: Beyond the Art of Nature
Inspired by nature yet transcending it, synthetic mRNA is being redesigned beyond the canonical architecture. This review highlights emerging forms—circular, branched, and self‐amplifying mRNAs—that expand stability, persistence, and functional control, illustrating how artificial mRNA is evolving into a new medium for programmable biological ...
Yuanzhe Cui +3 more
wiley +1 more source
Innovations in skin microphysiological systems for nonclinical testing and FDA modernization. [PDF]
Lee T, Kyung SY, Kwon M, Park B, Ko J.
europepmc +1 more source
Biomimetic Cell Membrane‐Coated MOFs System for Targeted Cancer Therapy
Biomimetic MOF‐based drug delivery nanoplatforms synthesized using liposomes or cell membranes as camouflage for multiple cancer therapeutics. ABSTRACT The integration of metal‐organic frameworks (MOFs) with cell membrane coatings has emerged as a revolutionary strategy to enhance the therapeutic efficacy of cancer nanomedicine.
Qilu Wu +6 more
wiley +1 more source
Reply to Urbina, F. Are Estrogens Involved in the Earlier Onset of Psoriasis in Girls? Comment on "Cassalia et al. How Hormonal Balance Changes Lives in Women with Psoriasis. <i>J. Clin. Med.</i> 2025, <i>14</i>, 582". [PDF]
Cassalia F +5 more
europepmc +1 more source
A Laminating Strategy to Manyfold Enhance the Elastic Stretchability of Stretchable Electronics
We propose a laminating strategy that laminates a thick‐polymer layer onto the thin‐ribbon metallic structure. Using serpentine structures on soft and hard substrates as representative cases, this approach increases elastic stretchability by 3.5‐fold and 2.3‐fold.
Zanxin Zhou +6 more
wiley +1 more source
Procedural Pain and Situational Anxiety in Pediatric Patients: A Narrative Review of Assessment Tools. [PDF]
Wojciechowska-Urbanek A +2 more
europepmc +1 more source

