Organic solvent‐free lipid nanoparticles featuring PEtOx‐based stealth lipids enable efficient mRNA and CRISPR‐Cas9 delivery while exhibiting markedly improved biocompatibility compared with PEG‐based analogues. Their successful ex vivo and in vivo performance, combined with data‐driven formulation optimization, establishes a versatile platform that ...
Michael Streiber +21 more
wiley +1 more source
Biological fundamental functional units of meridians: mechanosensitive ion channels. [PDF]
Wang Y, Zhou X, He S.
europepmc +1 more source
The influence of skin physicochemical properties on electrical sensory sensitivity during transcutaneous electrical nerve stimulation in women. [PDF]
Witkoś J +4 more
europepmc +1 more source
Radiative Hybrid Nanofluid Flow Over a Porous Riga Surface: A Fuzzy–ANN Modeling Approach
ABSTRACT This study proposes a fuzzy–ANN model to investigate the nonlinear thermal transport in a tangent hyperbolic (Tanh) hybrid nanofluid flow past a porous Riga surface, considering the effects of Rosseland diffusion, chemical reactions, and internal volumetric heating.
Azad Hussain, Rabia Zetoon, Reeha Iqbal
wiley +1 more source
Peristaltic flow of sutterby nanofluid in a stenosed artery with ciliated endothelium and wall roughness under hall and ion slip effects. [PDF]
Mostapha DR, Eldabe Nabil TM, Abbas W.
europepmc +1 more source
Abstract Hypoglossal nerve or tongue protruding muscle stimulation is a current treatment option for obstructive sleep apnea. Thus, the present study analyzed 3D deformations of the volumetric enlarged and reduced tongue base upon oropharyngeal neuromuscular stimulation.
Sydney Chen +2 more
wiley +1 more source
The IL-23/-17 Axis in PsA: What Have We Learned in the Last 20 Years? [PDF]
Theodoridou F, Katsouli O, Fragoulis GE.
europepmc +1 more source
Humans and platyrrhines share a pattern of articular variance
Abstract Previous work has identified a pattern of articular shape variation in modern human limb joints, in which convex joint surfaces exhibit constrained variance relative to their more variable concave conarticulars. This pattern is notable given that joint morphogenesis is influenced by local biomechanical environments, which vary substantially ...
Haley Horbaly, Liam Zachary
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An exploratory, in-field, multimodal assessment of cervical function in adults following to high-altitude trekking with light backpack. [PDF]
Perpetuini D +5 more
europepmc +1 more source
Fascicle measurement methods do result in lengths that are significantly different
A recent comparison of the most prevalent methods for measuring fascicles, in situ measurement versus chemical digestion, concluded that the measurements are indistinguishable based on data from different conspecific individuals. However, our study of contralateral muscles of the same individuals shows that the methods clearly result in statistically ...
Katherine M. Clark +5 more
wiley +1 more source

