Simplified schematic for generation of the subcutaneous air pouch model in the rodent. On day 0 and 4, air is injected into the subcutaneous space on the dorsal surface of the rodent to generate a cavity analogous to a synovial joint. On day 6, monosodium urate (MSU) or calcium pyrophosphate (CPP) crystals are injected into the pouch to stimulate ...
Wenu Hewage+4 more
wiley +1 more source
Neuroimaging Biomarkers for Friedreich Ataxia: A Cross‐Sectional Analysis of the TRACK‐FA Study
Objective We aimed to quantify differences in the brain and spinal cord between Friedreich ataxia and controls, stratified by age and disease stage, including for the first time in young children. Methods TRACK‐FA is the largest prospective, longitudinal, multi‐modal neuroimaging study in Friedreich ataxia to date.
Nellie Georgiou‐Karistianis+33 more
wiley +1 more source
Objective Neuroimaging is routinely utilized to identify new inflammatory activity in multiple sclerosis (MS). A large language model to classify narrative magnetic resonance imaging reports in the electronic health record (EHR) as discrete data could provide significant benefits for MS research. The objectives of the current study were to develop such
Shane Poole+14 more
wiley +1 more source
Predicting ecology and hearing sensitivities in Parapontoporia—An extinct long‐snouted dolphin
Abstract Analyses of the cetacean (whale and dolphin) inner ear provide glimpses into the ecology and evolution of extinct and extant groups. The paleoecology of the long‐snouted odontocete (toothed whale) group, Parapontoporia, is primarily marine with its depositional context also suggesting freshwater tolerance.
Joyce Sanks, Rachel Racicot
wiley +1 more source
Information cocoons in online navigation. [PDF]
Hou L+5 more
europepmc +1 more source
Abstract Modularity and integration are key developmental properties and have remained central in evo‐devo research because of how they relate to evolvability. While modularity and integration have commonly been assessed with landmark‐based geometric morphometrics (GMM), other methods such as anatomical network analysis (AnNA) are increasingly being ...
Kevin K. Duclos+4 more
wiley +1 more source
Towards Smaller and Stronger: An Edge-Aware Lightweight Segmentation Approach for Unmanned Surface Vehicles in Water Scenarios. [PDF]
Han W, Zhao B, Luo J.
europepmc +1 more source
Who understands and how? - exploring nurses' perceptions of the readability and usability of instructions written by hospital pharmacists. [PDF]
Satokangas H, Kvarnström K, Tolonen HM.
europepmc +1 more source
Survey sabotage: Insights into reducing the risk of fraudulent responses in online surveys
Abstract Validity is a key element of many forms of research—particularly surveys, which are often used in health professions education research. A survey must accurately measure what it is intended to measure to be considered valid. This is becoming increasingly difficult in the age of artificial intelligence (AI), where “bots” (short for robots) are ...
James Bonnamy+3 more
wiley +1 more source
Empowering human research ethics committees to review genomics applications: evaluating the utility of a custom online education resource. [PDF]
McGahan E+13 more
europepmc +1 more source