Results 61 to 70 of about 21,283 (217)

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

Advanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou, Sisi Luo, Binliang Tang, Zhiqiang Liu, Yuchuan Zhou, Yicong Meng, Zhengmu Wu, Zheng Sun, Weihui Shi, Jianzhong Sheng, Chuanjin Yu, Zhenhua Li, Siyi Wei, Mo Zhang, Yujie Luo, Jing Yan, Xueyun Qin, Jiahang Mo, Chengliang Zhou, Jinsong Li, Hefeng Huang, Yifu Ding, Guolian Ding   +22 more
wiley   +1 more source

Issues in Evaluating Health Department Web-Based Data Query Systems: Working Papers [PDF]

, 2008
Compiles papers on conceptual and methodological topics to consider in evaluating state health department systems that provide aggregate data online, such as taxonomy, logic models, indicators, and design.
Daniel J. Friedman, R. Gibson Parrish
core  

The effect of the motion of the Sun on the light-time in interplanetary relativistic experiments

, 2008
In 2002 a measurement of the effect of solar gravity upon the phase of coherent microwave beams passing near the Sun has been carried out with the Cassini mission, allowing a very accurate measurement of the PPN parameter $\gamma$.
B Bertotti, Bertotti B, Bertotti B, Eddington A, L Iess, Landau L D, Mignard F, Moyer T D, N Ashby, Ni W-T, Ni W-T, Ni W-T, Ni W-T, Soffel M, Turyshev S G, Turyshev S G, Will C M   +16 more
core   +1 more source

Mechanostimulatory Cues Determine Intestinal Fibroblast Fate and Profibrotic Remodeling in a Physiodynamic Human Gut‐on‐a‐Chip

Advanced Science, EarlyView.
A healthy gut barrier shields underlying fibroblasts from luminal shear forces, illustrating that “good fences make good neighbors.” Barrier damage exposes fibroblasts to shear stress, inducing cell death and the emergence of stress‐adapted, profibrotic fibroblasts. Sustained shear exposure promotes the formation of stiff aggregates of mechanoadapative
Soyoun Min, Nam Than, Yong Cheol Shin, Elif G. Ertugral, Chandrasekhar R. Kothapalli, Olumuyiwa Awoniyi, Hyun Jung Kim   +6 more
wiley   +1 more source

A Trio Neural Model for Dynamic Entity Relatedness Ranking

, 2018
Measuring entity relatedness is a fundamental task for many natural language processing and information retrieval applications. Prior work often studies entity relatedness in static settings and an unsupervised manner. However, entities in real-world are
Nejdl, Wolfgang, Nguyen, Tu Ngoc, Tran, Tuan   +2 more
core  

Investigation of interaction design principles, for use in the design of online galleries [PDF]

, 2007
This research is the culmination of a four-year investigation and analysis into the principles of Interaction Design, particularly those that are found to be most suitable when designing and developing interactive navigation systems.
Havlik, M
core  

A Soft Robotic Model for Simulating Heart Valve Disease and Cardiac Interventions

Advanced Science, EarlyView.
This paper introduces a fully synthetic fabrication methodology for a soft robotic, in‐vitro model of the left‐heart, complete with a functioning mitral valve apparatus. With a view towards patient‐specific modeling, we demonstrate physiological flow and pressure waveforms, tunable mitral valve function with clinical imaging compatibility, and its use ...
James Davies, Emanuele Nicotra, Kefan Zhu, Chi Cong Nguyen, Bibhu Sharma, Adrienne Ji, Phuoc Thien Phan, Jingjing Wan, Patrick Pruscino, Hermione Truong, Jelena Rnjak‐Kovacina, Hoang‐Phuong Phan, Christopher Hayward, Nigel Hamilton Lovell, Thanh Nho Do   +14 more
wiley   +1 more source

Navigating the page: an academic guide to effective reading [PDF]

, 2009
This guide introduces you to the various reading styles that will help you get through your research most effectively.
opteam,
core  

Web Data Extraction, Applications and Techniques: A Survey

, 2014
Web Data Extraction is an important problem that has been studied by means of different scientific tools and in a broad range of applications. Many approaches to extracting data from the Web have been designed to solve specific problems and operate in ad-
Abel, Amalfitano, Balduzzi, Baumgartner, Baumgartner, Baumgartner, Baumgartner, Baumgartner, Baumgartner, Berger, Berthold, Bettencourt, Califf, Catanese, Chang, Chen, Chen, Chen, Collins, Conover, Crandall, Crescenzi, Crescenzi, Dalvi, Dalvi, De Meo, De Meo, Doan, Emilio Ferrara, Ferrara, Ferrara, Ferrara, Ferrara, Ferrara, Flesca, Freitag, Furche, Gatterbauer, Gatterbauer, Giacomo Fiumara, Gjoka, Gkotsis, Gottlob, Gottlob, Hammersley, Han, Hecht, Hsu, Irmak, Khare, Kim, Kinsella, Kleinberg, Kleinberg, Kohlschütter, Kokkoras, Kokkoras, Kokkoras, Krüpl, Kushmerick, Kwak, Laender, Liu, Manning, Masanès, Mathes, Meng, Mislove, Monge, Muslea, Oro, Pan, Pasquale De Meo, Perito, Phan, Plake, Rahm, Rahm, Reis, Robert Baumgartner, Sahuguet, Sarawagi, Schifanella, Selkow, Shi, Soderland, Szomszor, Turmo, Vosecky, Wang, Wang, Weikum, Wilson, Winograd, Yang, Ye, Zafarani, Zanasi, Zhai, Zhang, Zhang   +100 more
core   +1 more source

Integrating Spatial Proteogenomics in Cancer Research

Advanced Science, EarlyView.
Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang, Yang Wu, Feng Zhang, Parthiban Periasamy, Haiyue You, Denise Goh, Rachel Elizabeth Ann Fincham, Xin Ning, Danping Wu, Lu Liu, Ying Jiang, Zhiwen Qian, Joe Yeong, Yan Zhang   +13 more
wiley   +1 more source