Results 1 to 10 of about 393,164 (224)

Skull and vertebral bone marrow are myeloid cell reservoirs for the meninges and CNS parenchyma

Science, 2021
Getting around the blood–brain barrier The meninges comprise three membranes that surround and protect the central nervous system (CNS). Recent studies have noted the existence of myeloid cells resident there, but little is known about their ontogeny and
A. Cugurra, Tornike Mamuladze, Justin Rustenhoven, Taitea Dykstra, Giorgi Beroshvili, Zev J. Greenberg, Wendy Baker, Zachary Papadopoulos, Antoine Drieu, Susan M. Blackburn, M. Kanamori, S. Brioschi, Jasmin Herz, Laura G. Schuettpelz, M. Colonna, Igor Smirnov, J. Kipnis   +16 more
semanticscholar   +1 more source

Cerebrospinal fluid regulates skull bone marrow niches via direct access through dural channels

Nature Neuroscience, 2022
It remains unclear how immune cells from skull bone marrow niches are recruited to the meninges. Here we report that cerebrospinal fluid (CSF) accesses skull bone marrow via dura–skull channels, and CSF proteins signal onto diverse cell types within the ...
J. Mazzitelli, Leon C. D. Smyth, Kevin A Cross, Taitea Dykstra, Jerry Sun, Siling Du, Tornike Mamuladze, Igor Smirnov, Justin Rustenhoven, J. Kipnis   +9 more
semanticscholar   +1 more source

Cerebrospinal fluid can exit into the skull bone marrow and instruct cranial hematopoiesis in mice with bacterial meningitis

Nature Neuroscience, 2022
Interactions between the immune and central nervous systems strongly influence brain health. Although the blood–brain barrier restricts this crosstalk, we now know that meningeal gateways through brain border tissues facilitate intersystem communication.
Fadi E. Pulous, Jean C. Cruz-Hernández, Chongbo Yang, Ζeynep Kaya, Alexandre Paccalet, G. Wojtkiewicz, Diane E. Capen, Dennis Brown, Juwell W. Wu, Maximilian J. Schloss, Claudio Vinegoni, Dmitry Richter, Masahiro Yamazoe, M. Hulsmans, Noor Momin, J. Grune, David Rohde, C. McAlpine, Peter R. Panizzi, R. Weissleder, Dong-Eog Kim, F. Swirski, Charles P Lin, M. Moskowitz, M. Nahrendorf   +24 more
semanticscholar   +1 more source

Pineal metastasis as first clinical manifestation of colorectal adenocarcinoma: case report [PDF]

Arquivos de Neuro-Psiquiatria, 1999
Cerebral metastases from colorectal adenocarcinomas occur in 8% of the cases. Diagnosis is usually made when primary disease and widespread metastases are already known.
RICARDO RAMINA, MAURÍCIO COELHO NETO, WAGNER M. MARIUSHI, WALTER O. ARRUDA   +3 more
doaj   +1 more source

Chordomas and chondrosarcomas of the skull base: treatment and outcome analysis in a consecutive case series of 24 patients

World Journal of Surgical Oncology, 2021
Background We present our 9-year consecutive case series of skull base chordomas and chondrosarcomas from a UK tertiary referral centre, discussing treatments offered and outcomes.
Christopher Metcalfe, Jameel Muzaffar, Kevin Kulendra, Paul Sanghera, Simon Shaw, Amjad Shad, Natarajan Saravanappa, Alessandro Paluzzi, Shahzada Ahmed   +8 more
doaj   +1 more source

Skull Base Osteomyelitis: A Comprehensive Imaging Review

American Journal of Neuroradiology, 2021
SUMMARY: Skull base osteomyelitis is a relatively rare condition, generally occurring as a complication of advanced otologic or sinus infection in immunocompromised patients.
P. Chapman, G. Choudhary, A. Singhal
semanticscholar   +1 more source

Acoustic properties across the human skull

bioRxiv, 2021
Transcranial ultrasound is emerging as a noninvasive tool for targeted treatments of brain disorders. Transcranial ultrasound has been used for remotely mediated surgeries, transient opening of the blood-brain barrier, local drug delivery, and ...
T. Riis, Taylor D. Webb, J. Kubanek
semanticscholar   +1 more source

Polymorphism at codon 31 of CDKN1A (p21) as a predictive factor for bevacizumab therapy in glioblastoma multiforme

BMC Cancer, 2023
Glioblastoma (GBM), a prevalent and malignant brain tumor, poses a challenge in surgical resection due to its invasive nature within the brain parenchyma.
Wen-Yu Cheng, Chiung-Chyi Shen, Yea-Jiuen Liang, Ming-Tsang Chiao, Yi-Chin Yang, Wan-Yu Hsieh, Cheng-Hui Lin, Jun-Peng Chen   +7 more
doaj   +1 more source

The Frontal Sinus and Frontal Recess: Anatomical, Radiological and Surgical Concepts

International Archives of Otorhinolaryngology, 2020
Introduction The frontal sinus (FS) is the most complex of the paranasal sinuses due to its location, anatomical variations and multiple clinical presentations.
Camila S. Dassi, Flávia R. Demarco, João Mangussi-Gomes, Raimar Weber, Leonardo Balsalobre, Aldo C. Stamm   +5 more
doaj   +1 more source

Endonasal endoscopic surgical treatment of craniopharyngiomas in adult patients. Our experience

Ukrainian Neurosurgical Journal, 2023
Objective: to estimate the results of surgical treatment of adult patients with craniopharyngiomas (CP), who underwent endoscopic endonasal surgical treatment. Materials and methods.
Mykola O. Guk, Andriy A. Chukov
doaj   +1 more source