ABSTRACT Background Pseudomonas aeruginosa is an opportunistic pathogen in cystic fibrosis‐related chronic rhinosinusitis (CF‐CRS) that produces phenazine metabolites pyocyanin and 1‐hydroxyphenazine (1‐HP), which may have detrimental effects on mitochondria, reactive oxygen species (ROS), Ca2+ signaling, and apoptosis.
Joel C. Thompson +8 more
wiley +1 more source
Artificial Intelligence-enabled Automatic Computed Tomography Segmentation for Craniomaxillofacial Surgery Using a Real Surgical Database. [PDF]
Wu S +7 more
europepmc +1 more source
Rationale of New Grading System: Central Compartment Atopic Disease
ABSTRACT Background Central compartment atopic disease (CCAD) has recently been recognized as a distinct phenotype within the spectrum of type 2–dominant chronic rhinosinusitis (CRS). Although international guidelines highlight polypoid changes in the central nasal cavity, standardized diagnostic and classification criteria are still lacking.
Ramón Moreno‐Luna +11 more
wiley +1 more source
Morphological and Radiologic Features of the Skull of a Juvenile Green Turtle (<i>Chelonia mydas</i>, Linnaeus, 1758) from Saint Kitts and Nevis, West Indies. [PDF]
Martonos CO +4 more
europepmc +1 more source
ABSTRACT Background Although shifts in nasal microbiota have been well‐documented in inflammatory upper airway conditions, microbiota tumor‐associated alterations remain uncharacterized. This study is the first to compare sinonasal microbiota profiles of patients with malignant tumors (MT), benign tumors (BT), and controls, offering insights into tumor‐
Evan A. Patel +13 more
wiley +1 more source
Controversies and challenges in outcome measurement for skull base surgery: A cross-pathology analysis. [PDF]
Abboud RS, Sviri GE.
europepmc +1 more source
Uncovering Cystic Fibrosis Carrier: Insights From a Heterozygous CFTR‐F508del Rabbit Model
ABSTRACT Background Chronic rhinosinusitis (CRS) is a heterogeneous inflammatory disorder frequently associated with impaired mucociliary clearance and bacterial infection. Individuals carrying a single cystic fibrosis transmembrane conductance regulator (CFTR) mutation exhibit partial CFTR dysfunction and are increasingly recognized as being at risk ...
Do‐Yeon Cho +9 more
wiley +1 more source
Behavioral implications of an embedded tyrannosaurid tooth and associated tooth marks on an articulated skull of <i>Edmontosaurus</i> from the Hell Creek Formation, Montana. [PDF]
Wyenberg-Henzler TCA, Scannella JB.
europepmc +1 more source
ABSTRACT Introduction Chronic rhinosinusitis (CRS) is an inflammatory disease with many different contributing factors, including bacterial infection. CRS patients are typically managed with medical therapies; however, these treatments frequently fail, leaving surgery as the only viable option.
Sintayehu Ambachew +8 more
wiley +1 more source

