Advanced Science, EarlyView.A novel “prof” cocktail therapy is designed. It screens antigens, selects personalized antigen panels, engineers optimized CAR‐Vδ1 T cells, and tests in patient‐derived GBM organoids, offering hope for effective CAR‐T drugs against heterogeneous solid tumors. Abstract Various challenges, including tumor heterogeneity and inadequate T cell infiltration,
Guidong Zhu +12 more
wiley +1 more source
Lizards and amphisbaenians (Reptilia, Squamata) from the middle Eocene of Mazaterón (Soria, Spain)
The Anatomical Record, EarlyView., 2023 Abstract The assemblage of lizards and amphisbaenians (Reptilia, Squamata) from the middle Eocene locality of Mazaterón (Spain) is described. Considering the rather limited material available for the study, the assemblage shows a moderate diversity with eight taxa corresponding to five different families.
Arnau Bolet
wiley +1 more source
3D-printed skull model for enhancing training in external ventricular drainage within medical education. [PDF]
3D Print MedScheidt K +7 more
europepmc +1 more source
Craniogenetic studies in Sus scrofa: With emphasis on the ‘orbitosphenoid’ problem
The Anatomical Record, EarlyView., 2023 Abstract The orbitosphenoid is a skeletal element of the endocranium of extant mammals. However, it has also been described in many of their fossil ancestors. Craniogenetic studies show that it is composed of two types of bone: first, the cartilaginous ala orbitalis and parts of the trabecular plate are transformed by endochondral ossification; second,
Wolfgang Maier, Ulla Lächele, Irina Ruf
wiley +1 more source
Advances and the Future of Skull Base Surgery. [PDF]
Balkan Med JVural A, Ferrari M.
europepmc +1 more source
The evolution of the skull and the cephalic muscles: a comparative study of their development and adult morphology. Part II. The Amphibia [PDF]
, 1944 H. Leighton Kesteven
openalex +1 more source
Chondro-Osseous Respiratory Epithelial Adenomatoid Hamartoma of the Skull Base: Report of a Case and Literature Review. [PDF]
J Neurol Surg RepTrent MS, Wang B, Kuan EC.
europepmc +1 more source
Phototherapy via Modulation of β‐Amyloid in Combating Alzheimer's Disease
Aggregate, EarlyView.This review introduces the light‐regulated Aβ aggregation, highlighting four applications: photodynamic therapy (PDT), photothermal therapy (PTT), photopharmacology, and photobiomodulation (PBM) systems. It also summarizes the current issues and proposes the prospects of photo‐induced modulation of Aβ aggregation and clearance as a therapeutic strategy
Yunhua Zhang +4 more
wiley +1 more source
Cranial morphology reveals a lack of phylogenetic signal and rapid adaptive radiation in the bat genus Molossus (Chiroptera: Molossidae). [PDF]
PLoS OneOlímpio APM +9 more
europepmc +1 more source