A combined machine learning and finite element modelling tool for the surgical planning of craniosynostosis correction. [PDF]
Antúnez Sáenz I +9 more
europepmc +1 more source
Generating golden Syrian hamsters with conditional alleles via zygote microinjection of CRISPR/Cas9
We established the first conditional knockout (cKO) model in the golden Syrian hamster by CRISPR/Cas9‐mediated genome editing. Cas9 protein, two sgRNAs, and a donor plasmid carrying loxP‐flanked exon 2 of the ApoF gene were microinjected into one‐cell embryos. The floxed allele was efficiently generated (up to 27%) and transmitted through the germline.
Wei Chen +16 more
wiley +1 more source
Building a predator: macroevolutionary patterns in the skull of abelisaurid dinosaurs. [PDF]
Pereyra EES +3 more
europepmc +1 more source
An in vivo assay for osteoclast activity using mouse calvaria
This study describes a novel method for measuring osteoclast‐mediated bone resorption in vivo using a mouse model. Localized injection of RANKL in a basement membrane matrix above the cranium induced osteoclast‐mediated bone resorption. Utilizing micro‐computed tomography and a semiautomated three‐dimensional analysis program, osteoclast resorption pit
Christopher Grieg +2 more
wiley +1 more source
Combination of Averaged Bregma-Interaural and Electrophysiology-Guided Technique Improves Subthalamic Nucleus Targeting Accuracy in Rats. [PDF]
Deng Z +5 more
europepmc +1 more source
Timing of Peri‐Ictal MRI Abnormalities in Status Epilepticus – One Size Does Not Fit All
Objective We aimed to investigate timing of occurrence of peri‐ictal MRI abnormalities – a potential risk biomarker of status epilepticus‐related cerebral injury (t2). Methods This prospective study enrolled adult patients with status epilepticus and acute magnetic resonance imaging (MRI); patients with peri‐ictal MRI abnormalities underwent follow‐up ...
Pilar Bosque Varela +12 more
wiley +1 more source
Influence of bone microstructure on ultrasound loss through skull-mimicking digital phantoms. [PDF]
Clinard S +4 more
europepmc +1 more source
Objective Amyotrophic lateral sclerosis (ALS) has a very specific neuroimaging signature, but the molecular underpinnings of the strikingly selective anatomic involvement have not elucidated to date. Accordingly, a large neuroimaging study was conducted with 258 participants to evaluate associations between patterns of neurodegeneration and focal ...
Marlene Tahedl +10 more
wiley +1 more source
Rare case of skull metastasis from endometrial carcinoma sparing lymph nodes: a case report. [PDF]
Aldulaijan D +3 more
europepmc +1 more source

