Results 311 to 320 of about 710,353 (381)

Olfactory Function Recovery in Endoscopic Transsphenoidal Pituitary Surgery

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
Key Points Olfactory flap preservation in transsphenoidal surgery (TSA) promotes early olfactory recovery. Objective olfactory function recovers faster than subjective olfaction following TSA. Olfactory‐specific and sinonasal olfactory‐specific quality of life (QOL) smell scores show divergent recovery timelines.
Sanjena Venkatesh   +7 more
wiley   +1 more source

Establishment of a humanized SCA2 mouse model carrying a CAA disruption preventing CAG repeat expansion in pathogenic genes

open access: yesAnimal Models and Experimental Medicine, EarlyView.
In this study, we established a mouse model in which CAG repeats do not undergo microsatellite instability (MSI) across generations. A humanized ATXN2 cDNA with four CAA interruptions within 73 CAG expansions was inserted into the Rosa26 locus of C57BL/6J mice. At the same time, a 23 CAG control mouse model was also generated.
Yao Zhang   +9 more
wiley   +1 more source

Dating burial practices and architecture at Lepenski Vir [PDF]

open access: yes, 2008
Bonsall, Clive   +5 more
core  

Insight into pericytes in glioblastoma angiogenesis: In vivo tracking by two‐photon microscopy and proteomic profiling

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Based on the inducible pericyte ablation model, we discovered that Pdgfrb+ pericytes regulate glioblastoma (GBM) growth. Using the pericyte lineage tracing model, we revealed their dynamic behavior during GBM angiogenesis. Proteomic analysis combined with pericyte RNA analysis based on human single‐cell data demonstrated cross‐species conserved ...
Qinghong Wang   +5 more
wiley   +1 more source

μ‐Opioid Receptor Dynamics in the Parameningeal Tissue During Migraine Attacks

open access: yesAnnals of Neurology, EarlyView.
Objective The possible impact of meningeal μ‐opioid receptor (μOR) binding in migraine remains unknown. This study investigated μOR availability in the cranial parameninges involved in migraine initiation via nociceptor activation. Methods We used positron emission tomography with [11C] carfentanil, and measured μOR availability in meninges and ...
Dajung J. Kim   +6 more
wiley   +1 more source

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