Results 21 to 30 of about 23,648 (291)
Primary Intraosseous Cavernous Hemangioma of the Clivus: Case Report and Review of the Literature
Primary intraosseous hemangiomas are benign, vascular malformations that account for approximately 1% of all primary bone neoplasms. These tumors are mostly found in vertebral bodies and are rarely seen in the calvarium, where they represent 0.2% of bony
Yakov Gologorsky +7 more
doaj +1 more source
Giant Petroclival Primary Intradural Chordoma: Case Report and Systematic Review of the Literature
Background Chordomas are rare, locally aggressive neoplasms thought to arise from notochordal remnants in the axial skeleton. Primary intradural chordomas are considered to be extremely rare.
Fahad AlOtaibi +3 more
doaj +1 more source
Background Plasmacytomas of the skull base are not commonly encountered in clinical practice, with few reported cases in the literature. They form part of the spectrum of plasma cell neoplasms and are classified as a solitary bone plasmacytoma if arising
Panduranga Seetahal-Maraj +2 more
doaj +1 more source
Sellar region extramedullary plasmacytoma – A rare skull base tumour
Plasma cell neoplasms can present either as multiple myeloma, or in
Yan Zheng Ho +2 more
doaj +1 more source
Background This is a case of mucormycosis originated osteonecrosis of the maxilla extended to the cranial base, initially suspected of malignancy. The patient was first suspected with osteolytic sarcomatous lesion but was later diagnosed with total ...
Young Long Park, Sura Cho, Jin-Woo Kim
doaj +1 more source
Historical Aspects and Surgical Nuances on the Craniocervical Approach to the Jugular Foramen
Context Tumors of the jugular foramen present a challenge to skull base surgeons. Their rarity, coupled with the complex anatomy of the region require exquisite knowledge and surgical technique.
Felipe Constanzo +3 more
doaj +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
DOI:10.3969/j.issn.1672⁃6731.2020.03 ...
Ren⁃zhi WANG
doaj
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Current situation and problems in skull base surgery
Because of the complex anatomic relationship and difficult treatment of skull base tumors, a multidisciplinary diagnosis and treatment mode (neurosurgery, otorhinolaryngology, head and neck surgery, oral and maxillofacial surgery, ophthalmology, plastic ...
Ren⁃zhi WANG, Ming FENG
doaj

