Results 91 to 100 of about 475,529 (364)
From Rigid to Soft Robotic Approaches for Neuroendoscopy
Advanced Robotics Research, EarlyView.Robotic assistance has had minimal impact on deep intraventricular surgeries, where small‐scale, precision, and reduced invasiveness can contribute to improved patient outcomes. Emerging technologies in rigid, soft, and hybrid robotics are reviewed to identify the most promising mechanisms for deep brain navigation in addition to an attempt to identify
Kieran Gilday +3 more
wiley +1 more source
Chondroid chordoma of the parapharyngeal space: A case report and review of literature
Acta Oto-Laryngologica Case Reports, 2020 Parapharyngeal space (PPS) tumors are a rare entity and account for less than 1% of all head and neck tumors. Although they exhibit a benign behavior, malignant neoplasms may arise from any of the structure contained in the space.
Nasser Waleed Alobida +4 more
doaj +1 more source
Prickle4 Drives Microenvironmental Remodeling and Resistance to Parp Inhibition in IDH‐Mutant Glioma
Advanced Science, EarlyView.IDH‐mutant gliomas exhibit sensitivity to PARP inhibitors (PARPi) owing to oncometabolite 2‐HG‐induced DNA repair defects. PARPi treatment induces resistance by upregulating Prickle4, which promotes VEGF‐driven angiogenesis. Combining PARPi veliparib with anti‐angiogenic lenvatinib blocks this pathway, causing tumor regression and prolonged survival in
Ju Yang +16 more
wiley +1 more source
Chondroma of Falx: Case Report of a Rare Condition [PDF]
Acta Medica Iranica, 2012 Chondroma is a benign tumor which mostly occurs in extremities but also sometimes in brain. Most intracranial chondromas arise from skull base, but chondroma of falx origin is a rare circumstance.
Shahryar Shahriarian +4 more
doaj +2 more sources
Radiographic measurements of the trachea in domestic short haired and Persian cats [PDF]
, 2011 Tracheal diameter can be assessed from a thoracic radiograph, with assessment of tracheal diameter in dogs based on ratios between tracheal diameter and a skeletal measurement – however reference ranges are not available for the cat.
Coleman, E. +3 more
core +1 more source
Advanced Science, EarlyView.In temporal lobe epilepsy, hippocampal APOE is markedly upregulated predominantly in microglia. APOE overexpression in microglia drives TLR4 and cGAS/STING‐dependent neuroinflammation, engages bidirectional crosstalk with neurons and astrocytes, increases neuronal excitability, and perturbs hippocampal lipid metabolism. These findings suggest that APOE‐
Jianwei Shi +10 more
wiley +1 more source
Paranasal sinuses malignancies : a 12-year review of clinical characteristics [PDF]
, 2016 Inadequate epidemiologic investigations of the paranasal sinuses malignancies prompted this retrospective study with special emphasis on a major group of 111 tumors.
Chamani, Mojtaba +3 more
core +1 more source
Advanced Science, EarlyView.Multi‐modality imaging strategy applied to PRV‐induced central nervous system infection enables dynamic visualization of cerebrovascular dysfunction, including hyperemia, hypoperfusion, and vascular remodeling. These changes are linked to microglial activation and impaired angiogenesis, providing mechanistic insight into PRV neuropathogenesis and ...
Shuting Ling +13 more
wiley +1 more source
Compromiso óseo seudo-mielomatoso en leucemia linfoide crónica
Revista de la Facultad de Medicina, 2000 It was described a case of chronic lymphocytic leukemia in a 75 year old man, with pseudoyelomatous osteolytic lesions in the skull, excluding other potential causes of osteolytic lesions in the clinical context of malignant lymphoproliferative ...
Octavio Martínez Betancur +1 more
doaj
Advanced Science, EarlyView.The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang +15 more
wiley +1 more source