Results 91 to 100 of about 200,246 (302)

A mouse model of mechanical stress injury to the basal ganglia using thermosensitive PNIPAM hydrogel for intracerebral hemorrhage research

Animal Models and Experimental Medicine, EarlyView.
In this study, we established a novel mouse model of intracerebral hemorrhage (ICH) by stereotactically injecting thermosensitive PNIPAM hydrogel into the internal capsule to impose localized mechanical stress on the corticospinal tract, which provides a straightforward and reproducible tool for preclinical studies on focal mechanical stress–induced ...
Mingxi Li, Yujie Chen, Rongsu Huang, Min Xia, Chao Mi, Yuan Tian, Peiwen Guo, Taotao Jin, Shilei Hao, Hua Feng, Yujie Chen, Zhi Chen   +11 more
wiley   +1 more source

Endoscopic endonasal transclival resection of a “pontine chordoma”: Technical case report

Interdisciplinary Neurosurgery, 2019
Clival chordomas represent very challenging neoplasms, due to their tendency to infiltrate bone, frequent recurrence, involvement of important neurovascular structures, and deep location. Lesions involving the brainstem remain difficult to access through
Weiqi Zhang, MD, Yue Bao, MD, Yong Wang, MD, Yibao Wang, MD   +3 more
doaj   +1 more source

Treatment of Cerebrospinal Fluid leakage in Skull Base Surgery [PDF]

, 2008
Objective : In various skull base approaches, the risk of cerebrospinal fluid (CSF) leakage exists and the leakage may lead to a life-threatening condition such as meningoencephalitis.
안정용, 장종희, 이규성, 홍창기, 심유식   +4 more
core  

The diagnostic value of the circadian rhythm gene KLF10 in anxiety‐depressive disorders and its neuroimmune regulatory mechanisms

Animal Models and Experimental Medicine, EarlyView.
This graphical abstract illustrates the protective role and molecular mechanism of the circadian rhythm‐related gene KLF10, identified as a diagnostic biomarker and therapeutic target in anxiety‐depressive disorder. Model establishment and phenotypes: An anxiety‐depression model was successfully established by chronic restraint stress combined with ...
Anlan Liu, Weifeng Guo, Jianxiang Li, Tiange Zhang, Dan Xu   +4 more
wiley   +1 more source

Mucinous Neoplasms

, 2015
Although interest in pancreatic pathology is very high in the radiological and gastroenterological communities, it is still the case that less is known about pathology of the pancreas than about liver pathology, for example.
D'ONOFRIO, Mirko, Capelli, Paola, MORANA, Giovanni, DE ROBERTIS LOMBARDI, Riccardo, Barbi, Emilio, TINAZZI MARTINI, Paolo, LUCHINI, Claudio, Crosara, Stefano   +7 more
core  

Adenosine monophosphate–activated protein kinase activation is associated with suppression of NLRP3 inflammasome–mediated neuroinflammation in a weight‐drop model of traumatic brain injury in Sprague–Dawley rats

Animal Models and Experimental Medicine, EarlyView.
This graphical abstract illustrates the study's schematic model. Adenosine monophosphate–activated protein kinase (AMPK) activators exhibited neuroprotection in the weight‐drop model of traumatic brain injury by improving cognition and regulating oxidative stress, microglial activation, and nucleotide‐binding oligomerization domain, leucine‐rich repeat,
Triveni Kodi, Paka Sravan Kumar, Krishnadas Nandakumar, Anoop Kishore   +3 more
wiley   +1 more source

Neurotransmitter‐Defined Degeneration Patterns in Sporadic and C9orf72‐Associated Amyotrophic Lateral Sclerosis: Predilection to GABAergic, Serotonergic, Opioid, Glutamatergic, Endocannabinoid, and Microglial Systems—Implications for Therapy Development

Annals of Neurology, EarlyView.
Objective Amyotrophic lateral sclerosis (ALS) has a markedly distinctive clinical and neuroradiological signature, with the preferential involvement of specific brain networks and the apparent sparing of others. The molecular underpinnings of the strikingly selective anatomical vulnerability have not been fully elucidated to date despite the potential ...
Marlene Tahedl, We Fong Siah, Jasmin Lope, Jennifer C. Hengeveld, Mark A. Doherty, Russell L. McLaughlin, Orla Hardiman, Ee Ling Tan, Alison Toomey, Jana Kleinerova, Peter Bede   +10 more
wiley   +1 more source

Solid parapharyngeal adenoid cystic carcinoma: apropos of a case

Acta Médica del Centro, 2013
Primary tumors of the parapharyngeal space are rare and account for only 0.5% of head and neck neoplasms. This space is an area similar to an inverted pyramid that begins at the base of the skull and extends to the greater horn of the hyoid bone, where ...
Rafael Michel Coca Granado, Yuniesky Jiménez Rodríguez, Johamel R. Ramos Valdés   +2 more
doaj  

Skull Base Cholesterol Granuloma: A Distinct Entity?

, 2015
Objective: Cholesterol granulomas (CG) are the most common benign lesions of the petrous apex (PA) and have very distinct computed tomography (CT) and magnetic resonance imaging (MRI) characteristics.
Telischi, Fred F, Angeli, Simon I, Dinh, Christine T, Truong, Kim, Morcos, Jacques, Goncalves, Stefania, Bhatia, Rita, Eshraghi, Adrien   +7 more
core   +1 more source

The petrotympanic canal (Huguier canal): Evolutionary, anatomical, and medical perspectives

The Anatomical Record, EarlyView.
Abstract The petrotympanic canal, traditionally referred to as Civinini's or Huguier's canal, represents an anatomical passage connecting the middle ear and temporomandibular joint (TMJ). Despite its early description, its structural complexity and functional significance have often been underestimated. In this study, we combined historical, anatomical,
Andrea Papini, Nicola Montemurro, Ferdinando Paternostro, Immacolata Belviso, Massimo Galli, Petra Martini, Licia Uccelli, Jacopo Moggi‐Cecchi, Gregorio Oxilia   +8 more
wiley   +1 more source