Results 51 to 60 of about 5,729 (273)

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler, Vivian Maas, Arian Taheri Amin, Jennifer Faber, Tamara Schaprian, Katharina Hill, Matthis Synofzik, Lisa H. Graf, Heike Jacobi, Manuela Lima, Ana F. Ferreira, Bart P. van de Warrenburg, Ilse H. J. Willemse, Dagmar Timmann, Andreas Thieme, Paola Giunti, Hector Garcia‐Moreno, Magda M. Santana, Jeannette Hübener‐Schmid, Elin H. Davies, Thomas Klockgether   +20 more
wiley   +1 more source

The method for approximate continuous Skyline query based on privacy protection in road network

Journal of Big Data
Existing road network continuous Skyline queries often neglect user location privacy and data privacy protection. This paper proposes a method for Approximate Continuous Skyline Query with Privacy Protection in road network (ACPP) environments to address
Song Li, Xiaolong Yang, Liping Zhang, Guanglu Sun   +3 more
doaj   +1 more source

Heaviest Induced Ancestors and Longest Common Substrings [PDF]

, 2013
Suppose we have two trees on the same set of leaves, in which nodes are weighted such that children are heavier than their parents. We say a node from the first tree and a node from the second tree are induced together if they have a common leaf ...
Gagie, Travis, Gawrychowski, Paweł, Nekrich, Yakov   +2 more
core  

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon, Hugues Chabriat, Dominique Hervé, Stéphanie Guey, Sophie Tezenas Du Montcel, Juliette Ortholand   +5 more
wiley   +1 more source

Efficient Computation of Skyline Queries Over a Dynamic and Incomplete Database

IEEE Access, 2020
Skyline queries rely on the notion of Pareto dominance, filter the data items by keeping only those data items that are the best, most preferred, also known as skylines, from a database to meet the user's preferences.
Ghazaleh Babanejad Dehaki, Hamidah Ibrahim, Fatimah Sidi, Nur Izura Udzir, Ali A. Alwan, Yonis Gulzar   +5 more
doaj   +1 more source

Caching Dynamic Skyline Queries [PDF]

, 2008
Given a query tuple q, the dynamic skyline query retrieves the tuples that are not dynamically dominated by any other in the data set with respect to q. A tuple dynamically dominates another, w.r.t. q, if it has closer to q's values in all attributes, and has strictly closer to q's value in at least one.
Dimitris Sacharidis, Panagiotis Bouros, Timos Sellis   +2 more
openaire   +1 more source

Role of Prednisone and 25‐Hydroxyvitamin D on Bone Mineral Density and Osteoporosis in Systemic Lupus Erythematosus

Arthritis Care &Research, EarlyView.
Objective We evaluated the role of 25‐hydroxyvitamin D (25[OH]D), prednisone, and other risk factors for bone mineral density (BMD) loss and osteoporosis in systemic lupus erythematosus (SLE). Methods We calculated the association between 25(OH)D levels and other potential risk factors and BMD measures (spine T scores) and osteoporosis (defined as a T ...
Nima Madanchi, Andrea Fava, Daniel W. Goldman, Laurence S. Magder, Michelle Petri   +4 more
wiley   +1 more source

RRR: Rank-Regret Representative

, 2018
Selecting the best items in a dataset is a common task in data exploration. However, the concept of "best" lies in the eyes of the beholder: different users may consider different attributes more important, and hence arrive at different rankings ...
Asudeh, Abolfazl, Das, Gautam, Jagadish, H. V., Nazi, Azade, Zhang, Nan   +4 more
core   +1 more source

A Skyline and ranking query odyssey: a journey from skyline and ranking queries up to f-skyline queries

, 2022
Skyline and ranking queries are two of the most used tools to manage large data sets. The former is based on non-dominance, while the latter on a scoring function. Despite their effectiveness, they have some drawbacks like the result size or the need for a utility function that must be taken into account.
openaire   +2 more sources

Does Long‐Term Lower Extremity Strength Training in Adults With Knee Osteoarthritis and Varus Alignment Reduce Knee Joint Loading During Gait?

Arthritis Care &Research, EarlyView.
Objective We examined whether 18 months of strength training in individuals with knee varus alignment and medial tibiofemoral osteoarthritis (OA) reduced knee joint loads during walking compared to an attention control group. Methods This study was a secondary analysis of a randomized clinical trial that compared the effects of strength training to a ...
Stephen P. Messier, Matthew N. Vigliotti, Paige E. Rice, Brian Pietrosimone, Shannon L. Mihalko, Edward H. Ip, Richard F. Loeser, David J. Hunter, Ali Guermazi, Ryan Hill, Santiago Saldana, Kim L. Bennell, Paul DeVita   +12 more
wiley   +1 more source