Results 181 to 190 of about 6,843 (278)

Quantitative proteomics identifies clusterin as a novel biomarker for atherosclerosis

Animal Models and Experimental Medicine, EarlyView.
This schematic illustrates the proposed mechanism. In advanced atherosclerotic lesions, upregulated CLU on the cell surface activates low‐density lipoprotein (LDL) receptor‐related protein 1 (LRP1). This interaction triggers the phosphorylation and activation of AKT.
Dengfeng Ding, Yingjie Zhang, Li Zhang, Xinou Zheng, Miaomiao Niu, Yunxiao Jia, Xuezhuang Li, Hua Chen, Chao Guo, Tao Jiang, Yuqiong Zhao   +10 more
wiley   +1 more source

On the Structure and Redox Behavior of Ni and Cu Single Atoms Supported on Carbon Nitride

Angewandte Chemie, EarlyView.
Magnetic and electronic spectroscopies, combined with DFT, establish the MN4 binding site of Ni and Cu single atoms on carbon nitride and elucidate their redox photochemistry. Ni undergoes geometry‐preserving, reversible M2+/M+ cycling, whereas Cu collapses to an irreversible low‐coordinate Cu+ state, suppressing photocatalysis.
Giovanni Colonnello, Ksenija Maver, Arianna Actis, Gaia Grando, Giacomo Filippini, Tiziano Montini, Michele Melchionna, Paolo Fornasiero, Lucia Nasi, Iztok Arčon, Lorenzo Donà, Bartolomeo Civalleri, Enrico Salvadori, Mario Chiesa   +13 more
wiley   +2 more sources

Screening of Protein Carbonylation Sites in Human Serum by Ion Mobility Mass Spectrometry. [PDF]

J Proteome Res
Rojas Echeverri JC, Milkovska-Stamenova S, Wagner U, Hoffmann R.   +3 more
europepmc   +1 more source

Sex‐Specific Genetic Architecture of ALS: Evidence of a Female Protective Effect?

Annals of Neurology, EarlyView.
Background Amyotrophic lateral sclerosis (ALS) shows sex differences in incidence and age of onset, yet the underlying biological mechanisms remain poorly understood. Methods We investigated sex‐specific genetic architecture in an Italian ALS cohort with whole‐genome sequencing (1,333 ALS cases, 755 controls).
Maurizio Grassano, Francesca Palumbo, Gabriele Mora, Salvatore Gallone, Giovanni De Marco, Ilaria Merulla, Claudia Paolantonio, Alessandra Maccabeo, Antonio Canosa, Umberto Manera, Rosario Vasta, Barbara Iazzolino, Marcella Testa, Giuseppe Fuda, Paolina Salamone, Giulia Marchese, Federico Casale, Cristina Moglia, Andrea Calvo, Giuseppe Borghero, Adriano Chiò   +20 more
wiley   +1 more source

Spatiotemporal dynamics of HIV-1 transmission networks in a major migration hub: integrated phylogenetic and molecular evidence. [PDF]

Front Microbiol
Zhu M, Chen J, Sun Z, Xu K, Zhang X, Wu S, Ye L, Xu X, Luo W.   +8 more
europepmc   +1 more source

CSF‐Compartmentalized Antibody Glycoprofiles in NMDAR Encephalitis Associate with Etiology and Functional Recovery

Annals of Neurology, EarlyView.
Objective To characterize Fc‐glycosylation profiles in patients with anti‐N‐methyl‐D‐aspartate receptor encephalitis (NMDARe) and assess their association with antibody compartmentalization (cerebrospinal fluid [CSF] vs serum), disease triggers (viral, tumor‐related or idiopathic), and 1‐year outcomes.
Laura Marmolejo, Claudia Papi, Chiara Milano, Esther Aguilar, Estibaliz Maudes, Ivana Duvnjak Orešković, Jerko Štambuk, Maja Pučić‐Baković, Gemma Olivé‐Cirera, Elianet Fonseca, Mar Guasp, Eugenia Martinez‐Hernandez, Helena Ariño, Takahiro Iizuka, Thais Armangué, Josep Dalmau, Marianna Spatola   +16 more
wiley   +1 more source

Translating Biomedical Research to Medical Devices: A Practical Guide and the Arteriovenous Graft Case Study

Advanced NanoBiomed Research, EarlyView.
Despite significant advances, most academic research fails to result in medical products that benefit patients. This guide shares five key steps to help researchers close that gap: set clear goals, test thoroughly, protect ideas, build diverse teams, and partner with industry.
Cristina Oldani, Nina Bono, Alice Caldiroli, Stefania Adele Riboldi, Gabriele Candiani   +4 more
wiley   +1 more source

Mechanistic insights into the anticancer, anti-inflammatory, and antioxidant effects of yellowfin tuna collagen peptides using network pharmacology. [PDF]

Narra J
Kairupan TS, Kapantow NH, Tallei TE, Niode NJ, Sanggelorang Y, Rotty LW, Wungouw HI, Kawengian SE, Fatimawali F, Maulydia NB.   +9 more
europepmc   +1 more source

Evidence for early circulation of the M1UK sublineage of Streptococcus pyogenes in Germany, 2015-2023. [PDF]

Emerg Microbes Infect
Rößler S, Boutin S, Berner R, Tomidis Chatzimanouil MK, Belheouane M, Rupp J, Merker M, Dresden GAS Study Group, Töpfner N, Nurjadi D.   +9 more
europepmc   +1 more source

Speciation, Structural Refinement, and Distribution of Ti Sites in Titanium Silicalite‐1 From 47/49Ti NMR Crystallography at 28.2 Tesla

Angewandte Chemie International Edition, EarlyView.
Titanium silicalite‐1 (TS‐1), used in industrial selective oxidation processes, depends on specific, yet still unresolved Ti sites, dispersed within the framework of an MFI‐zeolite. Applying high field (28.2 T) 47/49Ti NMR and 17O NMR spectroscopy for an array of TS‐1 catalysts enables the development of an NMR crystallography protocol and the ...
Christoph J. Kaul, Jonas Koppe, Lukas Lätsch, Michael Wörle, Sadig Aghazada, Jacob B. Holmes, Christina Wartmann, Mingji Zheng, Albrecht Berkessel, Trees De Baerdemaeker, Andrei‐Nicolae Parvulescu, Karsten Seidel, J. Henrique Teles, Alexander V. Yakimov, Christophe Copéret   +14 more
wiley   +1 more source