Results 151 to 160 of about 111,807 (207)

Mechanical Distraction Engages a Neuro‐Immune Program to Drive Regenerative Soft‐Tissue Healing in Ilizarov Bone Transport

open access: yesAdvanced Science, EarlyView.
Ilizarov bone transport accelerates healing of soft‐tissue wounds through unclear mechanisms. In a rat model, sustained mechanical distraction elicits calcitonin gene‐related peptide (CGRP)‐dominant sensory reinnervation, creating a niche that shifts immune cells from inflammatory to repair‐promoting states and speeds re‐epithelialization.
Yueliang Zhu   +9 more
wiley   +1 more source

Pyrolyzed Photoresist as a Continuous‐Tone Mask for Grayscale Lithography

open access: yesAdvanced Science, EarlyView.
True grayscale contact photolithography masks are created by pyrolysis of 3D multiphoton resist patterns. The resulting carbon masks retain micrometer‐scale patterned features while providing continuous‐tone optical transmission. This approach provides access to high‐quality grayscale lithography without requiring exotic materials or commercial mask ...
Tielyr D. Creason   +9 more
wiley   +1 more source

Advances in Josephson Junction Materials and Processes Toward Practical Quantum Computing

open access: yesAdvanced Science, EarlyView.
Emerging materials for quantum computing, including crystalline materials, two‐dimensional van der Waals materials, two‐dimensional electron gas systems, ferromagnets, and unconventional (e.g., d‐wave) superconductors, offer opportunities to engineer next‐generation Josephson junctions.
Hyunseong Kim   +11 more
wiley   +1 more source

Integrated Multiomic Analysis Reveals an EBV‐Associated MIF–SPP1+ Macrophage Axis Linking Tumor Stemness and Immune Dysfunction in Nasopharyngeal Carcinoma

open access: yesAdvanced Science, EarlyView.
This study maps how Epstein–Barr virus reshapes the cellular ecosystem of nasopharyngeal carcinoma. It identifies SPP1+ macrophages as partners of stemness‐associated tumor cells and dysfunctional T cells, links tumor‐derived MIF to macrophage recruitment and programming, and shows that macrophage‐derived SPP1 promotes tumorsphere formation and impairs
Guo‐Ying Liu   +15 more
wiley   +1 more source

Loss of Lepr in Fibroblasts Drives Tumor Development by Promoting Macrophage Infiltration

open access: yesAdvanced Science, EarlyView.
TNFα and TGFβ signaling reprograms Lepr+ fibroblasts toward a LeprnegMmphigh inflammatory CAF (iCAF) state, with downregulation of the Tcf21‐Lepr axis contributing to this transition. Lepr loss induces Csf3, which contributes to the enhanced macrophage‐recruiting capacity of these iCAFs, thereby promoting tumor development. Thus, inflammatory signaling
Manyu Song   +13 more
wiley   +1 more source

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