Results 41 to 50 of about 1,471,350 (340)

Numerical modeling of the effects of roughness on flow and eddy formation in fractures

open access: yesJournal of Rock Mechanics and Geotechnical Engineering, 2017
The effect of roughness on flow in fractures was investigated using lattice Boltzmann method (LBM). Simulations were conducted for both statistically generated hypothetical fractures and a natural dolomite fracture.
Scott Briggs   +2 more
doaj   +1 more source

Near-infrared spectroscopy (NIRS) as a useful tool to evaluate the treatment efficacy of positive airways pressure therapy in patients with obstructive sleep apnea syndrome (OSAS): A pilot study [PDF]

open access: yesJournal of Innovative Optical Health Sciences, 2014
In obstructive sleep apnea syndrome (OSA) the periodic reduction or cessation of breathing due to narrowing or occlusion of the upper airway during sleep leads to an impaired cerebral vascular autoregulation that is associated with an increased ...
Zhongxing Zhang   +4 more
doaj   +1 more source

Cerebral blood volume and oxygen supply uniformly increase following various intrathoracic pressure strains

open access: yesScientific Reports, 2017
Intrathoracic pressure (ITP) swings challenge many physiological systems. The responses of cerebral hemodynamics to different ITP swings are still less well-known due to the complexity of cerebral circulation and methodological limitation.
Zhongxing Zhang   +6 more
doaj   +1 more source

Personality features ina sample of psychophysiological insomnia patients [PDF]

open access: yesArquivos de Neuro-Psiquiatria, 2003
The personality is the way people express themselves inside the environment they live. Sleep, quality or quantity, is a way of this physical and psychological expression of well being.
Luciane Bizari Coin de Carvalho   +7 more
doaj   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

open access: yesFEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu   +6 more
wiley   +1 more source

Quantitative Changes in Muscular and Capillary Oxygen Desaturation Measured by Optical Sensors during Continuous Positive Airway Pressure Titration for Obstructive Sleep Apnea

open access: yesBiosensors, 2021
Obstructive sleep apnea (OSA) is a common sleep disorder, and continuous positive airway pressure (CPAP) is the most effective treatment. Poor adherence is one of the major challenges in CPAP therapy. The recent boom of wearable optical sensors measuring
Zhongxing Zhang   +3 more
doaj   +1 more source

Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins

open access: yesFEBS Open Bio, EarlyView.
We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó   +7 more
wiley   +1 more source

Treating restless legs syndrome in the context of sleep disordered breathing comorbidity

open access: yesEuropean Respiratory Review, 2019
Obstructive sleep apnoea (OSA) and restless legs syndrome (RLS) are two of the most prevalent sleep disorders and can coexist within the same patient. Nonetheless, the recognition of RLS among OSA patients has important clinical implications, since RLS ...
Sofía Romero-Peralta   +4 more
doaj   +1 more source

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