Results 71 to 80 of about 1,011,756 (317)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Pulmonary TherapyBackground Sleep disorders, including snoring and obstructive sleep apnea (OSA), are significant health concerns. OSA affects an estimated 4 million (8.5%) individuals in Vietnam, with 2.3 million suffering from moderate-to-severe conditions. Despite the
Sy Duong-Quy +29 more
doaj +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Physical active elderly women have longer total sleep time and better sleep quality: The roles of sleep logs and the visual analog scale [PDF]
, 2005 UNILAVRAS, Lavras, MG, BrazilUNIFESP, Ctr Clin & Sci Sleep, Dept Neurol, Sao Paulo, SP, BrazilUNIFESP, Dept Internal Med, Sao Paulo, SP, BrazilUNIFESP, Ctr Clin & Sci Sleep, Dept Neurol, Sao Paulo, SP, BrazilUNIFESP, Dept Internal Med, Sao Paulo, SP ...
Abe, Paulo Toshio +4 more
core
Effects of daytime food intake on memory consolidation during sleep or sleep deprivation. [PDF]
, 2012 Sleep enhances memory consolidation. Bearing in mind that food intake produces many metabolic signals that can influence memory processing in humans (e.g., insulin), the present study addressed the question as to whether the enhancing effect of sleep on ...
Fujita, Naoko +21 more
core +1 more source
Genetics of Sleep and Sleep Disorders [PDF]
Cell, 2011 Sleep remains one of the least understood phenomena in biology--even its role in synaptic plasticity remains debatable. Since sleep was recognized to be regulated genetically, intense research has launched on two fronts: the development of model organisms for deciphering the molecular mechanisms of sleep and attempts to identify genetic underpinnings ...
Sehgal, Amita, Mignot, Emmanuel
openaire +2 more sources
Aging and Cancer, EarlyView.This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source
Impulsivity and sleep disorders in schoolchildren [PDF]
, 2005 UNIFESP, Ctr Clin & Sci Sleep, Dept Neurol, Sao Paulo, SP, BrazilUNIFESP, Dept Internal Med, Sao Paulo, SP, BrazilUNIFESP, Ctr Clin & Sci Sleep, Dept Neurol, Sao Paulo, SP, BrazilUNIFESP, Dept Internal Med, Sao Paulo, SP, BrazilWeb of ...
Medeiros, Marilaine [UNIFESP] +8 more
core
Effects of Sleep Apnea on Nocturnal Free Fatty Acids in Subjects with Heart Failure [PDF]
, 2011 Study Objectives: Sleep apnea is common in patients with congestive heart failure, and may contribute to the progression of underlying heart diseae. Cardiovascular and metabolic complications of sleep apnea have been attributed to intermittent hypoxia ...
Luciano F. Drager +15 more
core +1 more source
Treating restless legs syndrome in the context of sleep disordered breathing comorbidity
European Respiratory Review, 2019 Obstructive sleep apnoea (OSA) and restless legs syndrome (RLS) are two of the most prevalent sleep disorders and can coexist within the same patient. Nonetheless, the recognition of RLS among OSA patients has important clinical implications, since RLS ...
Sofía Romero-Peralta +4 more
doaj +1 more source