Results 211 to 220 of about 164,986 (311)

Human hypoxia models in aerospace medicine: Potential applications for human pharmacological research

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aerospace medicine required controlled terrestrial models to investigate influences of altered atmosphere conditions, such as hypoxia, on human health and performance. These models could potentially be expanded to encompass disease conditions or treatment targets regulated through hypoxia or hypercapnia.
Titiaan E. Post   +4 more
wiley   +1 more source

Cumulative stressor exposure and cognitive functioning in late childhood: The role of inflammation

open access: yesBritish Journal of Developmental Psychology, EarlyView.
Abstract This study examined whether the experience of stressors since infancy is related to executive function and social communication in late childhood via inflammation, using data from 4457 participants of the Avon Longitudinal Study of Parents and Children (ALSPAC).
Izabella Polgar‐Wiseman   +2 more
wiley   +1 more source

Sex Hormones, Sex Hormone‐Binding Globulin and Sleep Problems in Females With Polycystic Ovary Syndrome: A Systematic Review and Meta‐Analysis

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Objective Sleep problems like obstructive sleep apnea (OSA) are common in polycystic ovary syndrome (PCOS), although the underlying mechanisms are not well understood. We aimed to determine the prevalence of sleep problems, synthesise and appraise studies analysing the associations between serum sex hormones, sex hormone‐binding globulin (SHBG)
Nur K. Abdul Jafar   +4 more
wiley   +1 more source

Exploring differences in signaling pathways of the circadian clock and neuromodulators in obstructive sleep apnea. [PDF]

open access: yesSci Rep
Turkiewicz S   +7 more
europepmc   +1 more source

Is It Possible to Screen for Primary Aldosteronism Effectively in Primary Care?

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Objective Primary aldosteronism (PA) is the commonest secondary cause of hypertension but case‐detection remains a challenge. Screening is usually performed in secondary care using an aldosterone:renin ratio (ARR) measurement. Here, we describe the outcomes of screening in primary care, in Oxfordshire, UK.
Harsha Anuruddhika Dissanayake   +9 more
wiley   +1 more source

Research‐Based Whole Genome Sequencing Identifies Biallelic Loss of Function Variants in DOCK3 Gene Causing DOCK3‐Related Disorder: The End of a Diagnostic Journey for This Family

open access: yesClinical Genetics, EarlyView.
ABSTRACT The DOCK3 gene (NM_004947.5) is located on chromosome 3p21.2 spanning 53 exons and encodes the dedicator of cytokinesis 3 protein. DOCK3 belongs to the family of guanine nucleotide exchange factors (GEFs) that activate GTPases. DOCK3 is expressed almost exclusively in the central nervous system and has been shown to promote axonal outgrowth ...
Khurram Liaqat   +7 more
wiley   +1 more source

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