Summary This study examined the change in weight at 6 months of naltrexone/bupropion (NB), a combination pharmacological therapy for weight management, in real‐world practice in Canada. The study was conducted through an observational, retrospective, single‐arm chart review of adult patients who attended the Wharton Medical Clinic in Ontario, Canada ...
Sean Wharton +4 more
wiley +1 more source
Respiratory effort burden measured by mandibular jaw movements as a digital marker with clinical insights in obstructive sleep apnea. [PDF]
Martinot JB +4 more
europepmc +1 more source
OSA Initiates Histone Lactylation That Drives PDE4B/FUS/AGT Axis to Pulmonary Hypertension
This study illustrates how chronic intermittent hypoxia (CIH) in obstructive sleep apnea (OSA) leads to hypertension via increased oxidative stress and mitochondrial dysfunction in pulmonary artery smooth muscle cells (PASMCs), causing glycolytic dysregulation. Lactate accumulation enhances histone lactylation, upregulating phosphodiesterase 4B (PDE4B),
Li Yang +12 more
wiley +1 more source
The Association Between Obesity, Obstructive Sleep Apnea, and Postoperative Complications in Breast Reduction Patients: A Propensity Score-Matched Analysis. [PDF]
Zontag N, Skorochod R, Wolf Y.
europepmc +1 more source
This systematic review identifies and categorizes the spectrum of non‐epileptic paroxysmal events in Rett syndrome. Respiratory disturbances, behavioural episodes, and motor events were the most commonly reported. Improving clinician awareness and diagnostic clarity is key to avoiding unnecessary treatment and enhancing quality of life for individuals ...
Natasha Bhatti, Daniel E. Lumsden
wiley +1 more source
Association of the weight-adjusted waist index and obstructive sleep apnea in adults. [PDF]
Pang S, Huang H, Zhu Y, Wu M.
europepmc +1 more source
Abstract Aims The timing of physical activity may influence metabolic health through interactions with circadian rhythms, yet its role in type 2 diabetes mellitus (T2DM) development is unclear. We investigated associations between time‐of‐day‐specific physical activity and incident T2DM, and whether theoretically reallocating activity from morning to ...
Marvin Y. Chong +8 more
wiley +1 more source
Effect of Stellate Ganglion Block on Postoperative Pain in Patients with Obstructive Sleep Apnea Syndrome: A Randomized Controlled Trial. [PDF]
Zhao L, Shen X, Li Y, Xu X, Zhan L.
europepmc +1 more source
The Impact of National Health Insurance Expansion on Suspected Obstructive Sleep Apnea: A Nine-Year Single-Center Study. [PDF]
Lee H, Lee E.
europepmc +1 more source
Obstructive sleep apnea in children: prevalence and association with overweight and obesity. [PDF]
Ingolfsdottir I +7 more
europepmc +1 more source

