Results 91 to 100 of about 18,828 (264)

Do symptoms and signs of temporomandibular disorders have an association with breathing pattern: a cross-sectional study on Turkish children and adolescents

BMC Oral Health
Background This paper aimed to explore the prevalence of temporomandibular disorders (TMDs) signs/symptoms, and to investigate the possible link between signs/symptoms of TMDs and mouth breathing (MB) by evaluating along with other risk factors, in a ...
Mehmed Taha Alpaydin, Tugce Alpaydin, Damla Torul   +2 more
doaj   +1 more source

Age and Nocturnal Polyuria in Nocturia: A Multicenter Voiding Diary Cohort Study

Neurourology and Urodynamics, EarlyView.
ABSTRACT Introduction Although the prevalence of nocturnal polyuria (NP) increases with age, the mechanisms underlying age‐related changes in voiding patterns and the daytime–nighttime distribution of urine volume remain unclear. Given that the severity of nocturia and bladder function may differ across age groups, age‐specific voiding profiles require
Kota Kawase, Yoshinori Nishino, Kanako Matsuoka, Shunta Makabe, Ryo Tanji, Hiroki Hoshino, Kei Kawada, Kousei Miwa, Masayuki Tomioka, Tomoki Taniguchi, Koji Iinuma, Yuki Tobisawa, Keita Nakane, Yoshiyuki Kojima, Takahiko Mitsui, Takuya Koie   +15 more
wiley   +1 more source

Effects of exercise on sleep symptoms in patients with severe obstructive sleep apnea

Jornal Brasileiro de Pneumologia
Objective: To investigate the extent to which exercise is associated with symptoms in patients with severe obstructive sleep apnea (OSA). Methods: We included subjects with an apnea-hypopnea index (AHI) > 30 events/h who completed validated sleep and ...
Roberto Pacheco da Silva, Denis Martinez, Kelly Silveira da Silva Bueno, Jhoana Mercedes Uribe-Ramos   +3 more
doaj   +1 more source

Circadian rhythms and chronotherapy in Alzheimer's disease: Mechanisms and therapeutic implications

Neuroprotection, EarlyView.
Circadian dysregulation contributes to Alzheimer's disease through sleep disruption, clock‐gene dysfunction, neuroinflammation, impaired proteostasis, and metabolic imbalance. These alterations promote cognitive decline and disease progression, while circadian biomarkers and chronotherapeutic interventions offer opportunities for precision diagnosis ...
Bivek Singh, Filippo Pigazzani, Roberto Manfredini   +2 more
wiley   +1 more source

SURMOUNT‐REAL UK: A Pragmatic Randomized Clinical Trial to Assess the Effectiveness of Tirzepatide in Adults With Obesity

Obesity, EarlyView.
ABSTRACT Objective SURMOUNT‐REAL UK will evaluate the effectiveness of tirzepatide when offered in addition to standard‐of‐care (SoC) in adults with Class I obesity (BMI ≥ 30 and ≤ 34.9 kg/m2) and without diabetes in a UK primary care setting. Methods A 5‐year, phase 4, multicenter, open‐label, pragmatic randomized clinical trial is enabled through ...
Martin K. Rutter, Julie Mount, J. Martin Gibson, Joanne Webb, Cheryl Marler, Catherine Reed, Mugdha Gore, Wenyu Ye, Elisa Gomez Valderas, John Wilding, Naveed Sattar, Melanie J. Davies, Kamlesh Khunti, Richard Haynes, Rachel L. Batterham   +14 more
wiley   +1 more source

Wernicke's Encephalopathy Following Semaglutide Treatment for Obesity: A Systematic PRISMA Review of Case‐Based Evidence

Obesity, EarlyView.
ABSTRACT Objective Glucagon‐like peptide‐1 receptor agonists are increasingly prescribed for obesity. Although generally considered safe, marked appetite suppression and persistent gastrointestinal adverse effects may increase the risk of nutritional deficiencies.
Janice Bidesie, Erik Oudman
wiley   +1 more source

Oral GLP‐1RA TERN‐601 for Adults With Obesity/Overweight: Placebo‐Controlled, Multiple‐Ascending‐Dose, Phase 1 and 2 Studies

Obesity, EarlyView.
ABSTRACT Objective The safety, tolerability, pharmacokinetics, and efficacy of TERN‐601, a once‐daily, oral small‐molecule glucagon‐like peptide‐1 (GLP‐1) receptor agonist, were studied in Phase 1 and 2 clinical studies. Methods The Phase 1 (28‐day) and Phase 2 (12‐week), randomized, double‐blind, placebo‐controlled, multiple‐ascending‐dose studies ...
W. Timothy Garvey, Julio Rosenstock, Harold E. Bays, Douglas Denham, Anita Kohli, Melanie Haines, Christopher Jones, Ellen Kwan, Erin Castelloe, Tonya Marmon, Emil Kuriakose, Cara Nelson   +11 more
wiley   +1 more source

CHARGE Syndrome: What an Otolaryngologist Should Know—A Systematic Review and Meta‐Analysis

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To synthesize the prevalence of otolaryngologic manifestations in CHARGE syndrome (CS) to support otolaryngologists in delivering comprehensive management. Data Sources PubMed/MEDLINE, Embase, and Google Scholar were searched for English‐ and French‐language studies published from January 1980 through January 2025.
Camille Caron, Massil Badji, Camille Prigent, Alix Pincivy, Erika Mercier, Mathieu Bergeron   +5 more
wiley   +1 more source

Comparative Meta‐Analysis of Complications of Maxillomandibular Advancement for OSA versus Orthognathic Surgeries for Dentofacial Deformities

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Maxillomandibular advancement (MMA) surgeries for obstructive sleep apnea (OSA) and orthognathic surgeries for dentofacial deformities (DFDs) are both complex procedures with distinct indications. This meta‐analysis and systematic review aimed to compare complications and recovery metrics between these surgeries. Data Sources CINAHL,
Mohamed Faisal Kassir, Angelica Walker, Lauren A. Howser, Allen Huang, Sami I. Nassar, Shaun A. Nguyen, Mohamed Abdelwahab   +6 more
wiley   +1 more source

Perioperative Adverse Events in Primary Palatoplasty: “Risk Factors and Impact on Care Escalation in a Multicenter Cohort”

Pediatric Anesthesia, EarlyView.
ABSTRACT Background Patients undergoing palatoplasty experience perioperative adverse events. Identifying risk factors for perioperative adverse events and escalation of care may improve outcomes. Methods Pediatric patients undergoing primary palatoplasty were included in this retrospective observational study performed at two academic children's ...
Febina Padiyath, Elizabeth M. O'Brien, Jennifer Nam, Paula Hu, Nishil Mehta, Marc Parris, Anthony Alexander, Ashley Hodges, Goretti Chiang, Vinícius Caldeira Quintão, Ricardo Vieira Carlos, Gabriel Soares de Sousa, Asif Padiyath, Susan C. Nicolson, John Fiadjoe, Oksana A. Jackson, Lisa K. Lee, Annery G. Garcia‐Marcinkiewicz   +17 more
wiley   +1 more source