Results 111 to 120 of about 1,044,100 (299)
Nocturnal oxygen therapy in obstructive sleep apnoea: a systematic review and meta-analysis
European Respiratory ReviewObstructive sleep apnoea is characterised by recurrent reduction of airflow during sleep leading to intermittent hypoxia. Continuous positive airway pressure is the first-line treatment but is limited by poor adherence. Nocturnal oxygen therapy may be an
Su Latt Phyu +3 more
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Development of a nalmefene formulation suitable for a community‐use auto‐injector
British Journal of Clinical Pharmacology, EarlyView.Aim Time to onset of reversal is critical when treating opioid‐induced respiratory depression and hypoxia. This study aimed to develop a formulation of the opioid antagonist nalmefene with an increased absorption rate and reduced time to onset of reversal following intramuscular administration. Methods Several absorption enhancers were screened in rats,
Alessandra Cipriano +6 more
wiley +1 more source
Treatment of obstructive and central sleep apnoea in heart failure: practical options
European Respiratory Review, 2007 Sleep apnoea, both central and obstructive disordered breathing, commonly occurs in patients with heart failure. Obstructive sleep apnoea occurs both in systolic and diastolic heart failure and is best treated with nasal positive airway pressure devices.
S. Javaheri
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British Journal of Clinical Pharmacology, EarlyView.Aims The glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) semaglutide and liraglutide are approved for chronic weight management. Both drugs also have favourable effects on the risk of developing diabetes and cardiovascular disease (CVD) compared with placebo, but their comparative effectiveness for these outcomes is unclear.
Ethan J. Cannon +7 more
wiley +1 more source
SLEEP APNOEA SYNDROME AND CARDIOVASCULAR DISEASE: A MODERN VIEW
Российский кардиологический журнал, 2012 This review presents the modern evidence on the association between sleep apnoea syndrome and cardiovascular disease. Among other aspects, the recently discovered mechanisms linking sleep apnoea and the development of atherosclerosis, coronary heart ...
I. G. Gordeev +2 more
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OBSTRUCTIVE SLEEP APNOEA IN CHILDREN
Slovenska pediatrija, 2020 Obstructive breathing disorders in sleep are a common problem in children that can have serious cardiovascular, neurocognitive, and metabolic consequences.
Nina Božanić Urbančič
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The Lancet Respiratory Medicine, 2019 BACKGROUND The evidence base for the treatment of mild obstructive sleep apnoea is limited and definitions of disease severity vary. The MERGE trial investigated the clinical effectiveness of continuous positive airway pressure in patients with mild ...
Alison J. Wimms +22 more
semanticscholar +1 more source
British Journal of Clinical Pharmacology, EarlyView.Hypertension in obesity represents a major global health challenge, closely linked to the global epidemics of obesity, type 2 diabetes and metabolic dysfunction. Excess adiposity contributes to elevated blood pressure through multiple, interrelated mechanisms, including activation of the renin–angiotensin–aldosterone system, sympathetic nervous system ...
Christina Antza +12 more
wiley +1 more source
Diagnostic algorithm of snore and sleep apnea in pations with nasal and pharyngeal obstruction
RUDN Journal of Medicine, 2016 The article presents diagnostic algorithm of snore and sleep apnea in ENT practice. Investigation of 81 patients with signs of nasal and pharyngeal obstruction revealed that 29 of them had obstructive sleep apnoea, 52 - primary snore without apnoea.
V I Panin, N A Pikhtileva
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The effect of adenotonsillectomy for childhood sleep apnoea on cardiorespiratory control
ERJ Open Research, 2016 The efficacy of adenotonsillectomy for relieving obstructive sleep apnoea symptoms in children has been firmly established, but its precise effects on cardiorespiratory control are poorly understood.
Mathias Baumert +7 more
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