Results 211 to 220 of about 43,382 (283)

Tumor Organoids: Breakthroughs in Clinical Decision Making, Drug Development, and Translational Advances Beyond Conventional Models

Med Research, EarlyView.
ABSTRACT Tumor organoid models are revolutionizing cancer research by bridging the translational gap between conventional two‐dimensional cell cultures and animal models. This Editorial thoroughly explores the fundamental innovations of patient‐derived organoid technology.
Yimao Wu, Ruowei Sun, Gokhan Zengin, Shuai Ren, Meng‐Yao Li   +4 more
wiley   +1 more source

Sleep architecture and quality and pain experience in individuals with persistent low back pain and asymptomatic controls. [PDF]

PLoS One
Wang X, Vendemia JMC, Kishman EE, Gilliam JR, Reynolds AM, Silfies SP.   +5 more
europepmc   +1 more source

Keyora Nutritional Neurology - Ashwagandha · The Clinical Matrix（4）: The Sleep Architecture Protocol: N3 Deep Wave Restoration & Glymphatic Clearance - Targeting "Non-Restorative Sleep": How Ashwagandha modulates GABAergic pathways to extend Slow-Wave Sleep and optimize neural waste removal

Xu Jin
openalex   +1 more source

Circadian Immunity and Vascular Inflammation in Cardiovascular Disease Chronotherapy Windows: Time for a Re‐Assessment

Med Research, EarlyView.
ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang, Ge Zhang, Tian‐Ding Liu, Tianshu Gu, Fengyi Yu, Pengyuan Xu, Wunan Mi, Xuanjiang Zhao, Qian Guo, Honglin Zheng, Taiqi Zhao, Qiang Li, Di Lu, Mingxuan Duan, Chaoyang Yu, Ruhao Wu, Shiqian Zhang, Haonan Zhang, Zeyu Wang, Youyang Zheng, Yan Xiao, Zenglei Zhang, Ge Zhang   +22 more
wiley   +1 more source

The Effect of CPAP Intervention on Sleep Architecture and Cognition in Alzheimer’s Disease Patients with Obstructive Sleep Apnea

Carmen Frías, Marta Almería, Judith Castejón, Cristina Artero, Giovanni Caruana, Andrea Elias, Karol Uscamaita, Virginia E. Hawkins, Nicola J. Ray, Maríateresa Buongiorno, Natàlia Cullell, Jerzy Krupiński   +11 more
openalex   +2 more sources

Stridor Is an Independent Risk Factor for Mortality and Disease Progression in Patients with Multiple System Atrophy

Movement Disorders, EarlyView.
Abstract Background and aim Stridor and sleep apnea syndrome (SAS) are common in multiple system atrophy (MSA). Retrospective cohort studies have yielded conflicting results regarding the consequences of stridor and SAS on the disease course. This study aimed to assess the prognostic significance of stridor and SAS, as well as the potential survival ...
Pauline Dodet, Cecile Proust‐Lima, Federico Sirna, David Bendetowicz, Giulia Lazzeri, Rachel Debs, Anna Delamarre, Margaux Dunoyer, Margherita Fabbri, Claire Georges, Imad Ghorayeb, David Grabli, Cécile Londner, Anne Pavy‐Le Traon, Maxime Patout, Olivier Rascol, Isabelle Arnulf, Alexandra Foubert‐Samier, Wassilios G. Meissner   +18 more
wiley   +1 more source

The impact of breaking up prolonged sitting with physical activity during simulated dayshifts and nightshifts on sleep architecture: a randomised controlled trial. [PDF]

Sci Rep
Gupta CC, Vitanege I, Ferguson SA, Vandelanotte C, Duncan MJ, Easton DF, Tuckwell G, Shay CA, Tucker P, Lastella M, Zerella M, Vincent GE.   +11 more
europepmc   +1 more source

Unraveling the Shared Genetic Architecture and Polygenic Overlap Between Loneliness, Major Depressive Disorder, and Sleep-Related Traits

Zainab Rehman, Abdul Aziz Khan, Jun Ye, Xianda Ma, Yifang Kuang, Ziying Wang, Zhaohui Lan, Qian Zhao, Jiarun Yang, Xu Zhang, Sanbing Shen, Weidong Li   +11 more
openalex   +1 more source

First In Vivo 23Na Human Imaging at 10.5 T Using a Combined Sodium‐Proton Transceiver Body Array

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To demonstrate the first in vivo human 23Na MRI at 10.5 T using a novel dual‐tuned transceiver body array and to evaluate a self‐gating approach for respiratory motion compensation, focusing on renal imaging. Methods A custom‐built eight‐channel 23Na‐loop 1H‐dipole transceiver array was designed, constructed, and characterized.
Simon Schmidt, Arcan M. Ertürk, Gregory J. Metzger   +2 more
wiley   +1 more source

The absence of Neuroligin-1 shapes wake/sleep architecture, rhythmic and arrhythmic activities of the electrocorticogram in female mice. [PDF]

Mol Brain
Areal CC, Lemmetti N, Leduc T, Bourguignon C, Lina JM, Bélanger-Nelson E, Mongrain V.   +6 more
europepmc   +1 more source