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Sleep Deprivation and the Epigenome [PDF]
Sleep deprivation disrupts the lives of millions of people every day and has a profound impact on the molecular biology of the brain. These effects begin as changes within a neuron, at the DNA and RNA level, and result in alterations in neuronal plasticity and dysregulation of many cognitive functions including learning and memory.
Marie E. Gaine +2 more
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The regulation of sleep and the response to sleep deprivation rely on multiple biochemical pathways. A critical connection is the link between sleep and metabolism.
Matthew S. Thimgan +4 more
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Sleep insufficiency is associated with various disorders; the molecular basis is unknown until now. Here, 14 males and 18 females were subjected to short‐term (24 h) sleep deprivation, and donated fasting blood samples prior to (day 1) and following ...
Chongyang Chen +13 more
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Five Hours Total Sleep Deprivation Does Not Affect CA1 Dendritic Length or Spine Density
Sleep is essential for long term memory function. However, the neuroanatomical consequences of sleep loss are disputed. Sleep deprivation has been reported to cause both decreases and increases of dendritic spine density.
Alvin T. S. Brodin +3 more
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Although previous studies have confirmed the association between relative deprivation and individual health, the relationship between and underlying mechanisms of relative deprivation and sleep quality have rarely been explored.
Meng Xiong +3 more
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Abstract Children's relationship with time in preschools is an under‐researched area. Young children rarely know how to measure time using a clock, but their experiences of time may contribute to understanding children's well‐being and debates about quality in preschools.
Kristín Dýrfjörð +3 more
wiley +1 more source
Microglia are involved in sleep/wake cycles and the response to sleep loss. Synaptic pruning by microglia is necessary for central nervous system circuit refinement and contributes to cognitive function.
Lu Wang +7 more
doaj +1 more source
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng +4 more
wiley +1 more source
Sleep deprivation is prevalent among athletes during competitions and is known to impair both motor and mental performance. This study aimed to assess how these performance decrements vary with melatonin supplementation.
Vinod Kumar G +3 more
doaj +1 more source
Functional Neuroanatomy of Sleep and Sleep Deprivation [PDF]
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Taber, Katherine H., Hurley, Robin A.
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