Results 61 to 70 of about 207,920 (304)

Augmented generation of protein fragments during wakefulness as the molecular cause of sleep: A hypothesis [PDF]

open access: yes, 2012
Despite extensive understanding of sleep regulation, the molecular-level cause and function of sleep are unknown. I suggest that they originate in individual neurons and stem from increased production of protein fragments during wakefulness.
Varshavsky, Alexander
core   +1 more source

Sleep Deprivation and Epilepsy [PDF]

open access: yesEpilepsy Currents, 2004
A patient with epilepsy should “spend the day awake and the night asleep. If this habit be disturbed, it is not so good … worse of all when he sleeps neither night nor day.”—Hippocrates ( 1 ) This review summarizes the data for and against sleep deprivation as a facilitator of epileptic seizures and interictal epileptiform discharges.
openaire   +2 more sources

Increased cortical excitability after selective REM sleep deprivation in healthy humans: a transcranial magnetic stimulation study [PDF]

open access: yes, 2013
REM sleep has antiepileptogenic properties whereas, its loss is known to have a proconvulsive role. However, the mechanisms underlying the proepileptogenic effects of REM sleep deprivation are yet not fully understood.
Albanese, M   +6 more
core   +1 more source

Inhibitory Decay and Supercritical Brain Dynamics During Sleep Deprivation

open access: yesAdvanced Science, EarlyView.
Sleep deprivation progressively shifts human brain dynamics from near‐critical toward supercritical states, as revealed by neuronal avalanche analysis of resting‐state fMRI. These changes track subjective sleep pressure rather than vigilance lapses and show marked network heterogeneity. A circuit model suggests that reduced inhibitory efficacy provides
Dai Zhang   +6 more
wiley   +1 more source

The effect of sleep deprivation on cortical excitability : a neuromagnetic approach [PDF]

open access: yes, 2017
Despite decades of study, no ironclad conclusion has been reached concerning the biological function of sleep in humans. Recent theories have proposed that sleep might play a role in maintaining cortical excitability at safe levels by downregulating ...
Rekola, Lauri
core  

The psychosocial toll of Dublin III on asylum seekers in the Netherlands

open access: yesAmerican Journal of Community Psychology, EarlyView.
Abstract The Dublin III Regulation determines which EU Member State is responsible for examining asylum claims, but its implementation carries significant consequences for those subjected to it. This study examines how Dublin III, as implemented in the Netherlands, affects asylum seekers' psychosocial wellbeing using Silove′s Adaptation and Development
Imen El Amouri
wiley   +1 more source

In vivo imaging of the central and peripheral effects of sleep deprivation and suprachiasmatic nuclei lesion on PERIOD-2 protein in mice. [PDF]

open access: yes, 2015
STUDY OBJECTIVES: That sleep deprivation increases the brain expression of various clock genes has been well documented. Based on these and other findings we hypothesized that clock genes not only underlie circadian rhythm generation but are also ...
Curie, T.   +3 more
core   +1 more source

B/ordering and healthcare access for migrants with precarious status: The role of healthcare workers in counteracting restrictive policies

open access: yesAmerican Journal of Community Psychology, EarlyView.
Abstract In Canada, precarious migration is largely invisibilized. Nonetheless, b/ordering greatly affects people's realities by limiting access to social rights. In Quebec, migrants with precarious status (MPS) do not have access to healthcare, although Quebec has a “universal” healthcare coverage.
Émilie Pigeon‐Gagné   +3 more
wiley   +1 more source

Altered brain-derived neurotrophic factor levels and oxidative stress in REM sleep deprivation: a rat model study

open access: yesBMC Neurology
Background Brain-derived neurotrophic factor (BDNF) is among the modulators associated with cognition and sleep that play a role in sleep disorders. This study aimed at investigating the effects of chronic sleep deprivation and REM sleep deprivation on ...
Yonca Coluk   +3 more
doaj   +1 more source

Sleep deprivation detected by voice analysis.

open access: yesPLoS Computational Biology
Sleep deprivation has an ever-increasing impact on individuals and societies. Yet, to date, there is no quick and objective test for sleep deprivation. Here, we used automated acoustic analyses of the voice to detect sleep deprivation.
Etienne Thoret   +4 more
doaj   +1 more source

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