Results 111 to 120 of about 3,871,182 (341)

Sleep analysis for elderly care using a low-resolution visual sensor network [PDF]

, 2015
Nearly half of the senior citizens report difficulty initiating and maintaining sleep. Frequent visits to the bathroom in the middle of the night is considered as one of the major reasons for sleep disorder.
A Heinrich, B Krüger, BB Nyan, D Foley, D Hodgins, DJ Foley, G Doblhammer, H Ni, J Lee, MG Umlauf, S Ancoli-Israel, U Anliker, V Metsis   +12 more
core   +2 more sources

The DEC2‐SCN2A Axis is Essential for the Anticonvulsant Effects of Cannabidiol by Modulating Neuronal Plasticity

Advanced Science, EarlyView.
This study identifies DEC2 as a critical transcriptional repressor of Scn2a that directly binds E‐box motifs in its promoter to regulate neuronal plasticity and epileptogenesis. Functional manipulation of DEC2 alters seizure susceptibility in vivo. Cannabidiol enhances this repression, unveiling a novel DEC2‐SCN2A axis underlying its anticonvulsant ...
Huifang Song, Yifan Wang, Lili Wang, Chang Guo, Shiqi Liu, Yi Rong, Jiawen Tian, Chao Peng, Yuying Shao, Zhixiong Ma, Na Li, Jingliang Zhang, Zijun Peng, Xu Yan, Hangwei Fa, Xinyue Ma, Jie Dong, Jinping Ji, Chen Yang, Haocheng Chen, Jing Liang, Qi Sun, Yang Yang, Weining Ma, Zhuo Huang   +24 more
wiley   +1 more source

Stress and Sleep Disorder

Experimental Neurobiology, 2012
The purpose of this study was to review potential, physiological, hormonal and neuronal mechanisms that may mediate the sleep changes. This paper investigates the literatures regarding the activity of the hypothalamic-pituitary-adrenal (HPA) axis, one of
Kuem-Sun Han, L. Kim, I. Shim
semanticscholar   +1 more source

Mental toughness, sleep disturbances, and physical activity in patients with multiple sclerosis compared to healthy adolescents and young adults

Neuropsychiatric Disease and Treatment, 2016
Dena Sadeghi Bahmani,1 Markus Gerber,2 Nadeem Kalak,1 Sakari Lemola,3 Peter J Clough,4 Pasquale Calabrese,5 Vahid Shaygannejad,6 Uwe Pühse,2 Edith Holsboer-Trachsler,1 Serge Brand1,2 1Psychiatric Clinics of the University of Basel, Center for ...
Sadeghi Bahmani D, Gerber M, Kalak N, Lemola S, Clough PJ, Calabrese P, Shaygannejad V, Pühse U, Holsboer-Trachsler E, Brand S   +9 more
doaj  

Wilson?s disease presenting as rapid eye movement sleep behavior disorder: a possible window to early treatment

Arquivos de Neuro-Psiquiatria, 2014
Objective To describe characteristics of REM sleep behavior disorder in Wilson’s disease. Method Questionnaire-based interviews (patients and relatives), neurological examinations, two-week prospective dream-diary, video-polysomnography, transcranial ...
Gotthard G. Tribl, Edson Bor-Seng-Shu, Mateus C. Trindade, Leandro T. Lucato, Manoel J. Teixeira, Egberto R. Barbosa   +5 more
doaj   +1 more source

Aromacare of Jasmine Increased Sleep Needs in Elderly [PDF]

, 2011
Introduction: Sleep disorder is one of the problems that faced by elderly. Progress of sleep change from time to time, sleep patterns during the aging experience different than younger people. Sleep patterns in elderly decreases according with increasing
Haryanto, J. (Joni), Kusnaidi, H. (Heri), Makhfudli, M. (Makhfudli)   +2 more
core  

A PERIOD3 variant causes a circadian phenotype and is associated with a seasonal mood trait. [PDF]

, 2016
In humans, the connection between sleep and mood has long been recognized, although direct molecular evidence is lacking. We identified two rare variants in the circadian clock gene PERIOD3 (PER3-P415A/H417R) in humans with familial advanced sleep phase ...
Fu, Ying-Hui, Hirano, Arisa, Hsu, Pei-Ken, Jones, Christopher R, Kaasik, Krista, Lin, Shu-Ting, McMahon, Thomas, Nishino, Seiji, Okuro, Masashi, Ptáček, Louis J, Saigoh, Kazumasa, Saigoh, Noriko, Sakai, Noriaki, Xu, Ying, Yamazaki, Maya, Zhang, Luoying   +15 more
core   +1 more source

Aging and the Spectral Properties of Brain Hemodynamics

Advanced Science, EarlyView.
As the brain ages, its metabolic demands decline—but not uniformly. Here, spectral slope flattening of resting‐state fMRI signals is proposed as a potential biomarker of pathologic brain aging. A subset of older adults diverges from youthful spectral and metabolic patterns, with changes linked to frontal white matter pathology and regional loss of ...
Ki Yun Park, Abraham Z. Snyder, Manu S. Goyal, Timothy O. Laumann, John J. Lee, Babatunde Adeyemo, Nicholas Metcalf, Andrei G. Vlassenko, Joshua S. Shimony, Eric C. Leuthardt   +9 more
wiley   +1 more source

Hubungan Antara Pemakaian Efavirenz Dengan Efek Samping Neuropsikiatri Pada Pasien Hiv/aids [PDF]

, 2015
Background: HIV/AIDS has been a global problem. Antiretroviral therapy is currently an effective therapy for HIV/AIDS. Efavirenz is an antiretroviral agent which commonly cause neuropsychiatric adverse events.Aim: To investigate the association between ...
Chasani, S. (Shofa), Ngestiningsih, D. (Dwi), Salsabila, F. (Farah), Sofro, M. A. (Muchlis)   +3 more
core  

Orosomucoid 1 Ameliorates Temporomandibular Joint Osteoarthritis by Maintaining Cartilage Homeostasis

Advanced Science, EarlyView.
The present study identified the key protein ORM1 through the proteomic analysis of synovial fluid samples from patients with temporomandibular joint osteoarthritis (TMJOA), and demonstrated the important role of ORM1 in maintaining cartilage homeostasis via the suppression of VIM/MAPK/MMP signalling.
Dahe Zhang, Yuxin Zhang, Simo Xia, Lu Chen, Pei Shen, Chi Yang   +5 more
wiley   +1 more source