Sleep Therapy as Immunomodulator of Elderly with Sleep Disorder [PDF]
Introduction: Sirep is one of the nursing intervention to solve sleep problems. Moreover, sirep as immunomodulator for cortisol level, IFN-γRa and IL-10 is still unknown.
Haryanto, J. (Joni) +1 more
core
Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source
Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz +3 more
wiley +1 more source
The sleep cycle: a mathematical analysis from a global workspace perspective [PDF]
Dretske's technique of invoking necessary conditions from information theory to describe mental process can be used to derive a version of Hobson's AIM treatment of the sleep/wake cycle from a mathematical formulation of Baars' Global Workspace model of ...
Wallace, Rodrick
core
Posterior Cortical Atrophy in the Asia‐Pacific: A Report From the PCA Asian Workgroup
ABSTRACT Objective Posterior Cortical Atrophy (PCA) is a distinct dementia syndrome primarily affecting spatial abilities and visual processing. It is associated with degeneration in the posterior part of the brain. PCA is subclassified into PCA‐pure and PCA‐plus syndromes based on consensus criteria.
Yuttachai Likitjaroen +11 more
wiley +1 more source
Evaluation of sleep problems in preeclamptic, healthy pregnant and non-pregnant women.
Sleep problems are common complaints among pregnant women. This study was designed to compare subjective sleep problems in non-pregnancy condition, healthy and preeclamptic pregnancy as a major complication of pregnancy.
Habibolah Khazaie +8 more
doaj
Extreme morning chronotypes are often familial and not exceedingly rare: the estimated prevalence of advanced sleep phase, familial advanced sleep phase, and advanced sleep-wake phase disorder in a sleep clinic population. [PDF]
Study objectivesReport the first prevalence estimates of advanced sleep phase (ASP), familial advanced sleep phase (FASP), and advanced sleep-wake phase disorder (ASWPD).
Ashbrook, Liza H +6 more
core
A Systematic Review and Meta‐Analysis of the Recurrence of Autoimmune Encephalitis
ABSTRACT Objective Autoimmune encephalitis (AE) is a disease with a potential for recurrence, and patients receive immunotherapy to prevent it. However, there is no consensus on the duration of immunotherapy. This study aimed to determine the recurrence rate and identify the risk factors for AE to provide guidance on the duration of immunotherapy ...
Shangkai Bai +5 more
wiley +1 more source
CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao +7 more
wiley +1 more source
Classifying Parkinson’s Disease With or Without Rapid Eye Movement Sleep Behavior Disorder Using Machine Learning-Based Analysis of Single-Lead Electrocardiogram [PDF]
Background and Objective Rapid eye movement sleep behavior disorder is a prodromal stage of alpha-synucleinopathy. Parkinson’s disease with rapid eye movement sleep behavior disorder is associated with more severe symptoms and cerebral pathology compared
Hye Jeong Lee +4 more
doaj +1 more source

