Results 121 to 130 of about 2,341,236 (258)

Pharmacotherapy only? Overview of available treatments for sleep disorders

Sleep disorders are one of the most common disorders of human well-being. They cause numerous health consequences, such as attention disorders, memory and recall difficulties, and motor disorders. The diagnosis of sleep disorders and the selection of the
Judyta Pluta, Mateusz Pluta, Michał K. Górski, Karolina Górska, Marta Buczkowska, Lucyna Ścisło, Katarzyna Antoniak-Sobczak, Górska, Karolina, Pluta, Mateusz, Górski, Michał K., Pluta, Judyta, Buczkowska, Marta, Antoniak-Sobczak, Katarzyna, Ścisło, Lucyna   +13 more
core   +1 more source

Entorhinal Astrocyte Transplants Restore Spatial Exploration and Alleviate Amyloid‐Beta Pathology in Alzheimer's Mice

Advanced Science, EarlyView.
Impaired MEC astrocytic Ca2+ signaling is associated with fragmented spatial exploration in AD mice. Region‐specific glial progenitor transplantation generates engrafted astrocytes that are accompanied by improved AQP4 polarization, reduced amyloid‐β‐associated pathology, attenuated neuroinflammation, preserved synaptic integrity, and ameliorated ...
Fengjuan Wu, Jihua Fan, Xiang Zhou, Zhiqi Yang, Mingyue Gong, Mingzhu Huang, Zhenlu Cai, Shaofan Yang, Teng Teng, Chuanyan Yang, Jin Li, Haoyu Wang, Shuangshuang Dai, Chunhai Chen, Xiaowei Chen, Manxia Wang, Kuan Zhang   +16 more
wiley   +1 more source

Transient Sleep Deprivation Induces Persistent Auditory Neuropathy via ROS‐Initiated Neuroinflammation and BK Channel Suppression

Advanced Science, EarlyView.
Sleep disturbance severity closely tracks hearing loss in a clinical cohort, yet the mechanistic link remains unclear. Acute sleep deprivation is shown to trigger transient cochlear oxidative stress that switches into a self‐sustaining neuroinflammatory state, suppressing BK channels and causing irreversible synaptopathy.
Dan Chen, Ying Ma, Lixuan Huang, Xin Chen, Fanliang Kong, Zhenzhou Qian, Mingyue Guan, Xinlin Wang, Yanyan Yang, Shasha Zhang, Peng Li, Renjie Chai   +11 more
wiley   +1 more source

Sleep disturbance in anxiety disorders

, 2013
Anxiety disorders are the most frequent psychiatric disorder with a lifetime prevalence of 29% in the general population. Anxiety-related hyperarousal can often lead to persistent circadian rhythm and sleep disturbances.
G. Manfredi, DEL CASALE, ANTONIO, SERATA, DANIELE, RAPINESI, CHIARA   +3 more
core  

Associations between severity of insomnia, attentional control and negative thought intrusions in healthy volunteers

, 2012
Recent research has found an association between insomnia and both negative affect and weakened attention control, yet despite this association and the high prevalence of sleep difficulties to be found in the general population, very little research has ...
Kenny, Louise Emma
core   +1 more source

Highly‐Time‐Resolved Measurements of Tryptophan's Distribution and Homeostatic Regulation in Live, Intact Animals

Advanced Science, EarlyView.
Using a novel, aptamer‐based biosensor, here we have performed 20‐s‐resolved, in situ measurements of plasma‐free tryptophan in the jugular veins of live rats (blue). This unprecedented time‐resolution provides insights into the regulation of tryptophan metabolism in live, intact animals.
Yuyang Wu, Chelsea N. Brown, Zeki Duman, Rose Mery Bakestani, Carl M. Kirkpatrick, Joao Hespanha, Tod Kippin, Kevin W. Plaxco   +7 more
wiley   +1 more source

Sex‐ and Time‐Resolved Physiological and Gut Ecosystem Responses to a Food‐Grade Microbiome‐Targeted Intervention in Collegiate Endurance Athletes

Advanced Science, EarlyView.
In collegiate endurance athletes, a 6‐week randomized CPYE intervention yielded time‐ and sex‐dependent shifts in field‐based cardiorespiratory, metabolic, and redox indices, accompanied by changes in gut multi‐omics profiles. An exploratory extension during intensified training generates hypotheses warranting future validation.
Meng Zhang, Le Ge, Kaiyang Liu, Yanrong Liu, Guolin Zhao, Lai‐Yu Kwok, Zheng Sun, Zhihong Sun, Wenyi Zhang   +8 more
wiley   +1 more source

Evaluation of daytime sleepiness and insomnia symptoms in OSA patients with a characterization of symptom-defined phenotypes and their involvement in depression comorbidity—a cross-sectional clinical study

Frontiers in Psychiatry
IntroductionRecent research highlights the significance of insomnia and sleepiness, shifting from obstructive sleep apnea (OSA) severity and sleep structure, in defining OSA phenotypes.ObjectivesThis study aimed to characterize insomnia and sleepiness ...
Agata Gabryelska, Szymon Turkiewicz, Piotr Białasiewicz, Filip Grzybowski, Dominik Strzelecki, Marcin Sochal   +5 more
doaj   +1 more source

Self‐Sustaining Sensing Systems: Integration Strategies and Signal–Power Matching in Energy‐Harvesting Electronics

Advanced Science, EarlyView.
Energy‐harvesting‐integrated sensors couple ambient energy conversion with sensing, processing, and wireless communication. This review organizes recent progress through integration architectures and operating principles, revisiting co‐packaged, monolithic, and co‐functional designs together with always‐on, event‐driven, and multi‐modal sensing modes ...
Taehyun Park, Ki‐Yoon Park, Yeonho Choi, Dong‐Myeong Shin, Hong‐Joon Yoon, Hocheon Yoo   +5 more
wiley   +1 more source

Sleep Disorders and Pregnancy

, 2010
Sleep patterns in women present different characteristics than in men. Menstrual cycle, puberty, menopause, and hormonal, emotional, and body heat changes emerging in pregnancy affect the sleep.
Ursavaş, Ahmet, Ahmet Ursavas
core   +1 more source