Results 301 to 310 of about 4,075,610 (383)
Buried Treasure? Overlooked and Newly Discovered Evolutionary Contributions to Human Brain Diseases
Recapitulative schema of different exploratory levels of the evolutionary impact on human neurological diseases. Clinical neuroscience focuses on the mechanisms of brain function, but this approach falls short of insights into how the central nervous system (CNS) evolved, both in health and disease.
Nico J. Diederich +20 more
wiley +1 more source
Sleep disorders and mental health: Understanding the cognitive connection. [PDF]
Akpoveta ED, Okpete UE, Byeon H.
europepmc +1 more source
Identification of New KCNT1‐Epilepsy Drugs by In Silico, Cell, and Drosophila Modeling
Objective Hyperactive KCNT1 potassium channels, caused by gain‐of‐function mutations, are associated with a range of epilepsy disorders. Patients typically experience drug‐resistant seizures and, in cases with infantile onset, developmental regression can follow.
Michael G. Ricos +9 more
wiley +1 more source
Sleep Disorders and Stroke: Pathophysiological Links, Clinical Implications, and Management Strategies. [PDF]
Rissardo JP +5 more
europepmc +1 more source
Turning Slowly Predicts Future Diagnosis of Parkinson's Disease: A Decade‐Long Longitudinal Analysis
Objective Wearable technology allows accurate measurement of turning while walking, with cross‐sectional studies indicating that difficulty turning presents even in preclinical phases of Parkinson's disease. The aim of our study was to quantify rate of change of turning performance in a cohort of older adults, and test whether turning decline can ...
Morad Elshehabi +9 more
wiley +1 more source
Exploring the Impact and Mechanisms of Coffee and Its Active Ingredients on Depression, Anxiety, and Sleep Disorders. [PDF]
Shi Z +10 more
europepmc +1 more source
Objective We aimed to evaluate the clinical utility of serum neurofilament light chain (sNfL) and cardiac troponin T (cTnT) in amyotrophic lateral sclerosis (ALS) and assess whether their combination improves diagnostic accuracy. Methods We retrospectively analyzed 293 ALS patients, 85 neurodegenerative disease controls, and 29 healthy controls.
Paula Lindenborn +6 more
wiley +1 more source

