Results 31 to 40 of about 132,673 (266)

The Natural History of Insomnia: Acute Insomnia and First-onset Depression

, 2013
Study Objectives: While many studies have examined the association between insomnia and depression, no studies have evaluated these associations 1) within a narrow time frame, 2) with specific reference to acute & chronic insomnia, and 3) using ...
Michael L. Perlis, Ellis, Jason, Ellis, JG, Bastien, Célyne, Espie, Colin, Bastien, Célyne H., Ellis, Jason G., Gardani, M, Bastien, CH, Célyne H. Bastien, Espie, CA, Perlis, Michael L., Colin A. Espie, Perlis, Michael, Gardani, Maria, Jason G. Ellis, Perlis, ML, Espie, Colin A., Maria Gardani   +18 more
core   +1 more source

Sleep Disturbance May Alter White Matter and Resting State Functional Connectivities in Parkinson's Disease

, 2017
Study Objectives: To clarify whether sleep disturbance would alter the patterns of structural and functional networks underlying cognitive dysfunction in patients with Parkinson's disease (PD).
이필휴, 손영호, 유한수, 정석종, 예병석   +4 more
core   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

The mediating role of sleep disturbance in the relationship between depression and cardiovascular disease

Frontiers in Psychiatry
BackgroundStudies suggest that both depression and disrupted sleep disturbance are linked to cardiovascular disease (CVD). However, the precise role of sleep disturbance in the connection between depression and CVD is poorly understood.
Feng Chen, Hao Lin, Yuansi Zhang, Yu Zhang, Linlin Chen   +4 more
doaj   +1 more source

The Nexus Between Sleep Disturbance and Delirium Among Intensive Care Patients

, 2021
Sleep in intensive care is hampered due to many factors; the clinical environment itself exacerbates sleep disturbance. Research suggests that interventions aimed at improving sleep quality have produced positive effects in reducing incidences and ...
van Haren, Frank, Delaney, Lori, Litton, Edward   +2 more
core   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Clinical Characteristics of HIV-Infected Patients With Sleep Disturbance [PDF]

, 2022
Objective This study aims to examine clinical characteristics and to identify possible risk factors of sleep disturbances in people living with HIV (PLWH).
김우정, 이은, 박경미
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Latent profiles and determinants of postoperative sleep quality in elective surgery patients

Scientific Reports
It is crucial to determine the potential subgroups of sleep disturbances in patients undergoing elective surgery based on the importance of symptom clusters and individual characteristics in order to develop targeted symptom management plans.
Binxu Yang, Jingjing Li, Dan Feng, Jing Gong, Yifei Yang, Xusihong Cai, Shuwen Huang, Lorna Kwai Ping Suen, Puzhong Gao, Qingde Wa, Jing Zhou   +10 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source