Longitudinal associations between sleep disturbance and disease severity in patients with COPD
Sleep Science and Practice, 2020 Background Sleep disturbance is a common complaint among patients with chronic obstructive pulmonary disease (COPD). Studies examining the associations between sleep disturbance and COPD severity have primarily been cross-sectional and produced ...
Faith S. Luyster +3 more
doaj +1 more source
The contribution of fatigue and sleepiness to depression in patients attending the sleep laboratory for evaluation of obstructive sleep apnea [PDF]
, 2011 Purpose: A high prevalence of depressive symptomatology has been reported amongst sufferers of obstructive sleep apnea (OSA), but it remains unclear as to whether this is due to their OSA or other factors associated with the disorder.
Downey, Luke +5 more
core +1 more source
Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization
Advanced Science, EarlyView.This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin +11 more
wiley +1 more source
Sleep Disturbance in Patients with Advanced Cancer [PDF]
, 2018 As cancer detection and treatment improves, people with cancer diagnoses are living longer. Cancer as a chronic illness has led to new demands to manage the side effects of the disease.
Frooman, Abigail
core
Advanced Science, EarlyView.This study reveals that maternal antibiotic exposure prior to conception disrupts intergenerational gut microbial succession. By enhancing maternal‐offspring microbial transmission, altering microbial developmental trajectories and increasing selective pressures during community assembly, these disturbances lead to persistent gut mucosal immaturity and
Yuzhu Chen +8 more
wiley +1 more source
Медицинский совет, 2016 Sleep disturbance (insomnia) is one of the most frequent state accompanying functional and organic disturbances in the human body. There are the following types of disturbances of this cycle: insomnia (a disturbance related to difficulties of the ...
N. V. Pizova
doaj +1 more source
HUBUNGAN ANTARA PEMAKAIAN EFAVIRENZ DENGAN EFEK SAMPING NEUROPSIKIATRI PADA PASIEN HIV/AIDS : Studi Kasus di RSUP dr. Kariadi Semarang [PDF]
, 2015 Background: HIV/AIDS has been a global problem. Antiretroviral therapy is currently an effective therapy for HIV/AIDS. Efavirenz is an antiretroviral agent which commonly cause neuropsychiatric adverse events.
Ngestiningsih, Dwi +2 more
core
A Spanish version of the athens insomnia scale
, 2012 Objectives To develop and validate a Spanish version of the Athens Insomnia Scale (AIS). Methods The AIS is designed to assess sleep difficulty and comprises eight items: the first five refer to the sleep disturbance and the last three to the daytime ...
Guilera Ferré, Georgina +2 more
core +1 more source
Impact of night-time symptoms in COPD : a real-world study in five European countries [PDF]
, 2013 Peer reviewedPublisher ...
Estruch, Jordi +5 more
core +2 more sources
Linearizing and Forecasting: A Reservoir Computing Route to Digital Twins of the Brain
Advanced Science, EarlyView.A new approach uses simple neural networks to create digital twins of brain activity, capturing how different patterns unfold over time. The method generates and recovers key dynamics even from noisy data. When applied to fMRI, it predicts brain signals and reveals distinctive activity patterns across regions and individuals, opening possibilities for ...
Gabriele Di Antonio +3 more
wiley +1 more source