Neuropsychiatric Symptoms Mimicking Dementia in a Patient Treated With Imatinib
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Tyrosine kinase inhibitors are the cornerstone of chronic myeloid leukemia treatment. Newer agents have more potency and a broader spectrum of action, but also a higher potential for neuropsychiatric side effects. We present a case of a patient on imatinib who developed progressive cognitive, mood, and behavioral alterations.
Ashley Jones +3 more
wiley +1 more source
Seeking for a fingerprint: analysis of point processes in actigraphy recording [PDF]
, 2016 Motor activity of humans displays complex temporal fluctuations which can be characterized by scale-invariant statistics, thus documenting that structure and fluctuations of such kinetics remain similar over a broad range of time scales.
Beldzik, E. +11 more
core +2 more sources
Adverse childhood experiences affect sleep duration for up to 50 years later.
Sleep, 2019 STUDY OBJECTIVES The main objective for this study was to assess the association of adverse childhood experiences (ACEs) and subsequent short sleep duration among adults.
K. Sullivan +4 more
semanticscholar +1 more source
Clinically Relevant Outcome Measures in Women With Adrenoleukodystrophy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Adrenoleukodystrophy is a rare inherited peroxisomal disease caused by pathogenic variants in the ABCD1 gene located on the X chromosome. Although the most severe central nervous system and adrenal complications typically affect only men with adrenoleukodystrophy, the majority of women develop myeloneuropathy symptoms in adulthood.
Chenwei Yan +3 more
wiley +1 more source
Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler +20 more
wiley +1 more source
Clustering of energy balance-related behaviors and parental education in European children : the ENERGY-project [PDF]
, 2013 Background:Recent research and literature reviews show that, among schoolchildren, some specific energy balance-related behaviors (EBRBs) are relevant for overweight and obesity prevention.
Brug, Johannes +8 more
core +5 more sources
Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito +14 more
wiley +1 more source
In-flight sleep as a pilot fatigue mitigation on long range and ultra-long range flights : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy at Massey University, Sleep/Wake Research Centre, Wellington, New Zealand [PDF]
, 2016 Objectives: Long range flights operate around the clock with long duty periods for pilots. To mitigate the effects of fatigue, these flights are operated by augmented crews, providing each pilot with the opportunity for sleep in on-board rest ...
Zaslona, Jennifer L
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick +19 more
wiley +1 more source
Frontiers in NeurologyBackgroundSedentary behavior is closely related to sleep disorders, and long-term lack of physical activity may disrupt circadian rhythms and increase the risk of sleep disorders; Excessive or insufficient sleep time may exacerbate health risks ...
Keke Ju, Na Liu, Ruikai Wu, Xiujiang Shi
doaj +1 more source