Results 221 to 230 of about 1,213,978 (351)

Ferroptosis‐Mediated Hippocampal Neuronal Loss Post‐mTBI: Chromatin Accessibility Profiling and Single‐Nucleus Transcriptomics

open access: yesAdvanced Science, EarlyView.
Hippocampal single ‐nucleus transcriptomes and chromatin accessibility after mild traumatic brain injury reveal dentate granule neuron vulnerability driven by ferroptosis. The c‐Jun–Tmsb4x–Slc2a2 axis modulates lipid peroxidation and iron dysregulation.
Manrui Li   +13 more
wiley   +1 more source

Integrating an Eco-Feedback Strategy to Enhance the Indoor Environmental Quality and Sleep Quality in Italian Bedrooms [PDF]

open access: gold
Michael T. Solomon   +5 more
openalex   +1 more source

Antifouling All‐Polymeric Microneedle Array for Long‐Term Wearable ECG Monitoring

open access: yesAdvanced Science, EarlyView.
A biocompatible, all‐polymeric MNEs designed for long‐term ECG monitoring is developed. Coated with PEDOT:Tos and zwitterionic SBMA, the MNEs offer ultra‐low impedance and antifouling properties. After 14 days of continuous use, the MNEs accurately detected PQRST complexes, highlighting its potential for long‐term, real‐time ECG monitoring in everyday ...
Ju Hyeon Kim   +4 more
wiley   +1 more source

CD27 and ICOS as Targets of PD‐1/PD‐L1 Signaling to Regulate Resident Memory CD8+ T‐Cell‐Mediated Pulmonary Protection and Pathology

open access: yesAdvanced Science, EarlyView.
Here it is revealed that the costimulatory receptors CD27 and ICOS are essential for the long‐term maintenance of PD‐1high CD8+ TRM cells following influenza infection. PD‐L1 blockade enhances the proliferation and activation of these cells through Nur77 activation downstream of the CD27/ICOS signaling axis, thereby boosting host immunity against ...
Yuanyuan Chen   +16 more
wiley   +1 more source

Effects of Bariatric Surgery on Sleep Disorder Symptoms and Sleep Quality. [PDF]

open access: yesObes Surg
Mutlu V   +6 more
europepmc   +1 more source

METTL5 Enables Immune Evasion of Liver Cancer via Chemokine mRNA Translation Regulation

open access: yesAdvanced Science, EarlyView.
METTL5 reshapes the tumor immune microenvironment through ribosome 18S rRNA m6A modification to regulate the translation of chemokine mRNA. Targeting METTL5‐mediated immunosuppression unleashes anti‐tumor immunity and improves the efficacy of anti‐PD‐1 therapy.
Shuang Li   +19 more
wiley   +1 more source

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