Results 171 to 180 of about 162,786 (309)

Automation of classification of sleep stages and estimation of sleep efficiency using actigraphy. [PDF]

Front Public Health, 2022
Kim H, Kim D, Oh J.
europepmc   +1 more source

Dual Physiological Barriers Bypassed by a Silk‐Based Supramolecular Protein Delivery Platform for Neuroinflammation Mitigation in Alzheimer's Disease

Advanced Science, EarlyView.
A supramolecular nanocomplex based on phenolic‐modified silk sericin is developed to deliver antioxidant enzymes across the blood–brain barrier and escape lysosomal degradation. This dual‐barrier‐crossing system reduces neuroinflammation and improves cognitive performance in Alzheimer's disease mouse model, offering a promising strategy for protein ...
Doudou Hu, Tiandong Li, Jian He, Yujian Jiang, Yeyuan Wang, Jingchen Sun   +5 more
wiley   +1 more source

EEG Feature Extraction for Automatic Sleep Stages Scoring

, 2007
Polysomnography (PSG) is the must common procedures used for diagnosis of sleep states. One of important task of PSG is sleep stages scoring. Sleeping stage of each 30 second segment is determined by sleep specialist, and scoring stages manually consumes
唐維志, Tang, Wei-Chih
core  

Daily changes in sleep stages and associated cardiovascular parameters during pregnancy: using a wearable device. [PDF]

Front Glob Womens Health
Guo Y, Xu Q, Narvaez L, Dutt N, Kehoe P, Qu A.   +5 more
europepmc   +1 more source

A two-branch trade-off neural network for balanced scoring sleep stages on multiple cohorts. [PDF]

Front Neurosci, 2023
Zhang D, Sun J, She Y, Cui Y, Zeng X, Lu L, Tang C, Xu N, Chen B, Qin W.   +9 more
europepmc   +1 more source

Targeting Endogenous Lipophagy: A Novel Strategy to Enhance MSC Osteogenesis and Mineralization for Senile Osteoporosis Therapy

Advanced Science, EarlyView.
Schematic representation of the role of lipophagy in bone mesenchymal stem cells(MSCs). In healthy MSCs, functional lipophagy efficiently degrades lipid droplets to support oxidative phosphorylation and cellular energy production, thereby facilitating osteogenic differentiation and matrix mineralization.
Chaoqiang Chen, Zhidong Liu, Yanhang Sun, Xiaojun Xu, Zhexiao Lan, Junhao Zhao, Peitao Xu, Guiwen Ye, Jinteng Li   +8 more
wiley   +1 more source

Autism and mild epilepsy associated with a de novo missense pathogenic variant in the GTPase effector domain of DNM1

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023
Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei, Elena Parrini, Claudia Bianchini, Maria Luisa Ricci, Renzo Guerrini   +4 more
wiley   +1 more source

Exploring cardiac autonomic dysfunction in synucleinopathies with parkinsonism through awake-sleep stages: a possible connection to cardiovascular death. [PDF]

BMJ Neurol Open
Limotai N, Somboon T, Suanprasert N, Rujirussawarawong S, Tumnark T, Unwanatham N, Limotai C.   +6 more
europepmc   +1 more source

Paternal Caffeine Exposure Programs Offspring Stress Vulnerability via Sperm Dlk1‐Dio3 Imprinting‐Directed Remodeling of a Novel Neural Circuit

Advanced Science, EarlyView.
The study elucidates that paternal preconception stress can drive offspring hyperresponsivity of the stress system via hypomethylation of a specific DNA region in sperm. This key link is confirmed in a cohort of prospective fathers: the epigenetic alteration is associated with elevated stress hormone levels.
Mengxi Lu, Gaole Dai, Sen Zhu, Shuai Zhang, Tingting Wang, Yuan Meng, Fang Yang, Xiaoyi Han, Hui Wang, Hao Kou, Dan Xu   +10 more
wiley   +1 more source

Associations of sleep-associated variants with wearable-derived sleep stages in the All of Us research program. [PDF]

Sleep
Chan IN, Nouraie SM, Chan SY, Kelly NJ.
europepmc   +1 more source