Results 41 to 50 of about 148,378 (289)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Automated scoring of pre-REM sleep in mice with deep learning

Scientific Reports, 2021
Reliable automation of the labor-intensive manual task of scoring animal sleep can facilitate the analysis of long-term sleep studies. In recent years, deep-learning-based systems, which learn optimal features from the data, increased scoring accuracies ...
Niklas Grieger, Justus T. C. Schwabedal, Stefanie Wendel, Yvonne Ritze, Stephan Bialonski   +4 more
doaj   +1 more source

Peripheral blood flow estimated by laser doppler flowmetry provides additional information about sleep state beyond that provided by pulse rate variability

Frontiers in Physiology, 2023
Pulse rate variability (PRV), derived from Laser Doppler flowmetry (LDF) or photoplethysmography, has recently become widely used for sleep state assessment, although it cannot identify all the sleep stages.
Zhiwei Fan, Zhiwei Fan, Yoko Suzuki, Like Jiang, Like Jiang, Satomi Okabe, Satomi Okabe, Shintaro Honda, Junki Endo, Takahiro Watanabe, Takashi Abe   +10 more
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

A multiplex visibility graph motif‐based convolutional neural network for characterizing sleep stages using EEG signals

Brain Science Advances, 2020
Sleep is an essential integrant in everyone’s daily life; therefore, it is an important but challenging problem to characterize sleep stages from electroencephalogram (EEG) signals.
Qing Cai, Jianpeng An, Zhongke Gao
doaj   +1 more source

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Sleep in the Quran and Health Sciences

Health, Spirituality and Medical Ethics, 2014
Background and Objectives: Sleep is a sign of the greatness of God. In this article sleep is described from Quran and modern health sciences. Methods: This is a qualitative systematic review. Data were gathered from the Quran, related Islamic narratives
Mohammad Reza Heidari, Reza Norouzadeh, Mohammad Abbasi   +2 more
doaj  

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Sleep Stability with Home Sleep Recording and Automatic Sleep Stage Analysis [PDF]

Sleep, 1990
Three home sleep recordings were conducted in 12 normal subjects using the Oxford Medilog 9000 system with automatic sleep stage analysis (SS90III). Each night was separated by 1 week. No significant differences were noted for any sleep parameter, with the mean intraindividual variation less than 20% for most parameters.
Sharpley, A, Solomon, R, Cowen, P
openaire   +3 more sources