Results 81 to 90 of about 549,762 (295)

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source

DeepSleepNet: a Model for Automatic Sleep Stage Scoring based on Raw Single-Channel EEG

, 2017
The present study proposes a deep learning model, named DeepSleepNet, for automatic sleep stage scoring based on raw single-channel EEG. Most of the existing methods rely on hand-engineered features which require prior knowledge of sleep analysis. Only a
Dong, Hao, Guo, Yike, Supratak, Akara, Wu, Chao   +3 more
core   +1 more source

Comparing the cardiac autonomic activity profile of daytime naps and nighttime sleep. [PDF]

, 2018
Heart rate variability (HRV) is a reliable technique to evaluate autonomic activity and shows marked changes across a night of sleep. Previous nighttime sleep findings report changes in HRV during non-rapid eye movement sleep (NREM), which have been ...
Mednick, Sara C, Naji, Mohsen, Whitehurst, Lauren N   +2 more
core   +3 more sources

Sleep stage dynamics in young patients with sleep bruxism [PDF]

Sleep, 2019
AbstractStudy ObjectivesWe hypothesized that sleep stage dynamics are different in patients with sleep bruxism (SB) and that these changes are associated with the occurrence of rhythmic masticatory muscle activity (RMMA).MethodsFifteen healthy controls and 15 patients with SB underwent overnight polysomnography.
Akifumi, Kishi, Shingo, Haraki, Risa, Toyota, Yuki, Shiraishi, Mayo, Kamimura, Masako, Taniike, Hirofumi, Yatani, Takafumi, Kato   +7 more
openaire   +2 more sources

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi, Caroline Gochanour, Seung Ho Choi, Hyunkeun Cho, Chelsea Caspell‐Garcia, Christopher Coffey, Michael Brumm, David‐Erick Lafontant, Yuge Xiao, Thomas Tropea, John Seibyl, Caroline Tanner, Charles S. Venuto, Karl Kieburtz, Lana M. Chahine, Kathleen L. Poston, Andrew Siderowf, Kenneth Marek, Tanya Simuni, The Parkinson's Progression Markers Initiative   +19 more
wiley   +1 more source

Adenosine Deaminase Polymorphism Affects Sleep EEG Spectral Power in a Large Epidemiological Sample [PDF]

, 2012
Slow wave oscillations in the electroencephalogram (EEG) during sleep may reflect both sleep need and intensity, which are implied in homeostatic regulation.
Azeredo Bittencourt, Lia Rita [UNIFESP], Guindalini, Camila [UNIFESP], Mazzotti, Diego Robles [UNIFESP], Santos-Silva, Rogerio [UNIFESP], Sato, Joao Ricardo, Souza, Altay Alves Lino de [UNIFESP], Tufik, Sergio [UNIFESP]   +6 more
core   +1 more source

Sleep Position and Sleep Stages: Evidence of Their Independence [PDF]

Sleep, 1998
Recently we conducted a first ontogenetic study of sleep positions in the human, which involved five groups of 10 subjects (5 males, 5 females) from each of the following age categories: 3-5 years, 8-12 years, 18-24 years, 35-45 years, 65-80 years. They slept for 4 consecutive nights in the laboratory. Sleep positions were recorded during 2 nights with
D, Lorrain, J, De Koninck
openaire   +2 more sources

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Utility of Sleep Stage Transitions in Assessing Sleep Continuity [PDF]

Sleep, 2010
Sleep continuity is commonly assessed with polysomnographic measures such as sleep efficiency, sleep stage percentages, and the arousal index. The aim of this study was to examine whether the transition rate between different sleep stages could be used as an index of sleep continuity to predict self-reported sleep quality independent of other commonly ...
Alison, Laffan, Brian, Caffo, Bruce J, Swihart, Naresh M, Punjabi   +3 more
openaire   +2 more sources

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown, Giulia Carli, Prabesh Kanel, Stiven Roytman, Jaimie Barr, Nicolaas I. Bohnen, Roger L. Albin   +6 more
wiley   +1 more source