Results 131 to 140 of about 1,958,798 (262)

The diagnostic value of the circadian rhythm gene KLF10 in anxiety‐depressive disorders and its neuroimmune regulatory mechanisms

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This graphical abstract illustrates the protective role and molecular mechanism of the circadian rhythm‐related gene KLF10, identified as a diagnostic biomarker and therapeutic target in anxiety‐depressive disorder. Model establishment and phenotypes: An anxiety‐depression model was successfully established by chronic restraint stress combined with ...
Anlan Liu   +4 more
wiley   +1 more source

The Rise of IGFBP4 in People with Obstructive Sleep Apnea and Multilevel Sleep Surgery Recovers Its Basal Levels. [PDF]

open access: yesDis Markers, 2021
Alterki A   +10 more
europepmc   +1 more source

Sleep deprivation of rats: The hyperphagic response is real

open access: yes, 2008
Study Objectives: Chronic sleep deprivation of rats causes hyperphagia without body weight gain. Sleep deprivation hyperphagia is prompted by changes in pathways governing food intake; hyperphagia may be adaptive to sleep deprivation hypermetabolism.
LE, Wei Wei   +3 more
core  

An Investigation of Sleep Macro‐ and Microarchitecture by APOE Genotype

open access: yesAnnals of Neurology, EarlyView.
Objectives Apolipoprotein E ε4 (APOE ε4), a robust genetic risk factor for Alzheimer's disease (AD) is associated with functional connectivity deficits and amyloid pathology in brain regions involved in sleep regulation. Thus, alterations in sleep architecture may be one pathway through which ε4 contributes to Alzheimer's disease vulnerability. However,
Gawon Cho   +6 more
wiley   +1 more source

Machine learning-based preoperative datamining can predict the therapeutic outcome of sleep surgery in OSA subjects. [PDF]

open access: yesSci Rep, 2021
Kim JY   +8 more
europepmc   +1 more source

Sleep disturbance impairs stroke recovery in the rat

open access: yes, 2011
STUDY OBJECTIVES: There is a lack of experimental evidence to support the hypothesis that sleep may modulate stroke outcome as suggested by clinical observations.
Cam, Ertugrul   +14 more
core   +1 more source

Therapeutic Prospects of Ketamine for Cataplexy in Narcolepsy Type 1: Evidence from a Human Case and a Murine Model

open access: yesAnnals of Neurology, EarlyView.
Narcolepsy type 1 is characterized by cataplexy, for which current treatments targeting monoaminergic, histaminergic, and GABAergic pathways may be ineffective or poorly tolerated. We report the case of a 34‐year‐old man with narcolepsy type 1, intolerant to standard therapies, who experienced marked and sustained cataplexy reduction with morning ...
Francois Ricordeau   +8 more
wiley   +1 more source

Cortisol levels and sleep patterns in infants with orofacial clefts undergoing surgery

open access: yesNeuropsychiatric Disease and Treatment, 2014
Andreas A Mueller,1,2 Nadeem Kalak,3 Katja Schwenzer-Zimmerer,1,2 Edith Holsboer-Trachsler,3 Serge Brand3,4 1Craniomaxillofacial Surgery, University of Basel and University Hospital of Basel, Basel, Switzerland; 2Hightech Research Center of ...
Mueller AA   +5 more
doaj  

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