Results 81 to 90 of about 1,958,798 (262)
Abstract Representation of Movement Parameters in Basal Ganglia Output
Advanced Science, EarlyView.The basal ganglia output provides a scalable velocity/position signal across behavioral contexts, supporting the idea that these variables are represented in the brain as abstract entities rather than as fixed changes in joint angles or specific sets of body effectors.
Ana Silvia Báez‐Cordero +3 more
wiley +1 more source
Agreement in the Scoring of Respiratory Events and Sleep Among International Sleep Centers [PDF]
, 2013 Study Objectives: the American Academy of Sleep Medicine (AASM) guidelines for polysomnography (PSG) scoring are increasingly being adopted worldwide, but the agreement among international centers in scoring respiratory events and sleep stages using ...
SAGIC Investigators +16 more
core +1 more source
Advanced Science, EarlyView.An integrated proteogenomic analysis of 44,137 predominantly European‐ancestry UK Biobank participants aged 40–69 years identifies 12 robust proteins associated with idiopathic pulmonary arterial hypertension. These proteins define a high‐mortality molecular endotype, support early detection and mortality prediction, reveal sex‐differential proteomic ...
Xinjie Lin +18 more
wiley +1 more source
A Novel BHLHE41 Variant is Associated with Short Sleep and Resistance to Sleep Deprivation in Humans
, 2014 Study Objectives: Earlier work described a mutation in DEC2 also known as BHLHE41 (basic helix-loop-helix family member e41) as causal in a family of short sleepers, who needed just 6 h sleep per night.
Dinges, David F +19 more
core +1 more source
Endowing Flexibility of Alveolar Type II Cells to Recapitulate Development From Lung Bud to Alveoli
Advanced Science, EarlyView.Adult human alveolar type 2 cells are chemically reprogrammed into expandable alveolar progenitor‐like cells that acquire bud tip‐like features during expansion and form organoids that mature into alveolar‐like structures. These organoids model influenza A virus infection and innate immune responses in vitro, while transplanted cells engraft ...
Hongqian Ma +18 more
wiley +1 more source
Nature and Science of Sleep, 2020 Bijia Song,1,2,* Yuanyuan Chang,1,* Yang Li,1 Junchao Zhu1 1Department of Anesthesiology, Shengjing Hospital of China Medical University, Shenyang, Liaoning, People’s Republic of China; 2Department of Anesthesiology, Friendship Hospital of Capital ...
Song B, Chang Y, Li Y, Zhu J
doaj
Advanced Science, EarlyView.ABSTRACT Beta‐amyloid peptide (Aβ)‐induced suppression of hippocampal GABAergic interneuron activity drives hyperexcitability, amyloid pathology, and cognitive impairment in Alzheimer's disease (AD), suggesting that enhancing hippocampal inhibition may be protective.
Rahmi Lee +3 more
wiley +1 more source
Advanced Science, EarlyView.Continuous molecular monitoring using electrochemical aptamer‐based sensors enables real‐time tracking of dynamic biomarkers with transformative potential for precision medicine. Achieving clinically relevant month‐long stability remains a central challenge due to multiple degradation pathways.
Shibo Liu, Xiangling Li, Wei Ouyang
wiley +1 more source
OTO OpenObjective Hypoglossal nerve stimulation in the US requires drug‐induced sleep endoscopy to exclude patients with complete concentric collapse. This is an expensive and time‐consuming requirement.
Jordan S. Weiner +10 more
doaj +1 more source
Free Recall of Word Lists under Total Sleep Deprivation and after Recovery Sleep
, 2012 Study Objectives: One task that has been used to assess memory effects of prior total sleep deprivation (TSD) is the immediate free recall of word lists; however, results have been mixed.
Pompeia, Sabine [UNIFESP] +6 more
core +1 more source