Results 121 to 130 of about 18,395,903 (215)

Molecular Basis for Activation to Inhibition Switching in Kv7.2 Channel Modulators

Angewandte Chemie, EarlyView.
The paper describes the serendipitous discovery of chemical manipulation allowing the activator‐to‐inhibitor switching in Kv7.2 channel modulators. The molecular determinants driving this switch have been rationalized by multidisciplinary investigation encompassing synthetic and analytical chemistry, in silico methods, cryo‐EM analysis ...
Tania Ciaglia, Giusy Carleo, Zhenni Yang, Francesca Di Matteo, Federica De Rosa, Gerardina Smaldone, Zhao‐Bing Gao, Marco D'Alì, Rita Turcio, Demin Ma, Veronica Di Sarno, Nannan Su, Salvatore Vincenzo Giofrè, Giacomo Pepe, Pietro Campiglia, Alessia Bertamino, Francesco Miceli, Jiangtao Guo, Nunzio Iraci, Carmine Ostacolo, Maurizio Taglialatela   +20 more
wiley   +2 more sources

FGF1-based Drugs for The Treatment of Obesity-related Complications

Shengwu huaxue yu shengwu wuli jinzhan
At present, the incidence of overweight and obesity has reached epidemic levels worldwide, which call a challenge to the prevention and control of chronic metabolic diseases.
JI Wei-Xiu, LI Meng, ZHAO Yun-Gang
doaj   +1 more source

Impulsivity and sleep disorders in schoolchildren

, 2005
UNIFESP, Ctr Clin & Sci Sleep, Dept Neurol, Sao Paulo, SP, BrazilUNIFESP, Dept Internal Med, Sao Paulo, SP, BrazilUNIFESP, Ctr Clin & Sci Sleep, Dept Neurol, Sao Paulo, SP, BrazilUNIFESP, Dept Internal Med, Sao Paulo, SP, BrazilWeb of ...
Medeiros, Marilaine [UNIFESP], Silva, Tatiana Almeida [UNIFESP], Souza, Adriana [UNIFESP], Prado, Lucila Bizari Fernandes do [UNIFESP], Barreto, Luciane de Andrade [UNIFESP], Canepa, Rezinilda Portela Meira [UNIFESP], Ferreira, Vanessa Ruotolo [UNIFESP], Carvalho, Luciane Bizari Coin de [UNIFESP], Prado, Gilmar Fernandes do [UNIFESP]   +8 more
core  

Body position and obstructive sleep apnea in children

, 2002
Study Objectives: In adults, sleep apnea is worse when the patient is in the supine position. However, the relationship between sleep position and obstructive apnea in children is unknown.
Li, Xianbin B. [UNIFESP], Xianbin Li, Lucila B. Fernandes do Prado, Prado, Lucila Bizari Fernandes do [UNIFESP], Richard Thompson, Marcus, Carole L., Carole L. Marcus, Thompson, Richard   +7 more
core   +1 more source

Implementing Indigenous Data Sovereignty in Australia: A Five‐Phase Framework for Indigenous Data Governance

Australian Journal of Social Issues, EarlyView.
ABSTRACT This article presents the development of a five‐phase Indigenous Data Governance (IDGov) Framework in Australia, focusing on partnerships between the Aboriginal Community Controlled Health Organisation (ACCHO) sector and non‐Indigenous health entities.
Jacob Prehn, Michael A. Guerzoni, Maggie Walter, Gawaian Bodkin‐Andrews, Bobby Maher   +4 more
wiley   +1 more source

A Tripartite Framework of Conflict-Induced Stress, Acoustic Hypervigilance, and Ramadan Observance as Convergent Determinants of Circadian Decoherence in Athletes

Nature and Science of Sleep
Wissem Dhahbi,1,2 Karim Chamari,3 Ismail Dergaa,4– 6 Khaled Trabelsi,7,8 Meriem Gaddas,9,10 Achraf Ammar,11– 13 Ahmed S BaHammam,14,15,* Helmi Ben Saad9,10,*1Research Unit "Sport Sciences, Health and Movement”, High Institute of ...
Dhahbi W, Chamari K, Dergaa I, Trabelsi K, Gaddas M, Ammar A, BaHammam AS, Ben Saad H   +7 more
doaj  

Barriers and Enablers for Effective Support Coordination in the National Disability Insurance Scheme

Australian Journal of Social Issues, EarlyView.
ABSTRACT Support coordinators act as intermediaries between the National Disability Insurance Scheme (NDIS) and participants, facilitating access to funded supports. To optimise outcomes, they must navigate NDIS complexities, identify services that meet individual needs and engage with diverse stakeholders.
Sharyn McDonald, Lee Cubis, Di Winkler, Jacinta Douglas   +3 more
wiley   +1 more source

Associations Between Salivary Cortisol, DHEA-S, and Alpha-Amylase and Longitudinal Sleep Disruption in Shift-Working Healthcare Professionals: A Pilot Study

Nature and Science of Sleep
Mohammed F Salahuddin,1 Karn Sukararuji,1,* Mahsa Sharifi,1,* Kingsley Anetor Francis Odia,1 Md Dilshad Manzar,2 Seithikurippu R Pandi-Perumal,3,4 Ahmed S BaHammam5,6 1Department of Pharmaceutical Sciences, School of Pharmacy & Health
Salahuddin MF, Sukararuji K, Sharifi M, Odia KAF, Manzar MD, Pandi-Perumal SR, BaHammam AS   +6 more
doaj  

Physical active elderly women have longer total sleep time and better sleep quality: The roles of sleep logs and the visual analog scale

, 2005
UNILAVRAS, Lavras, MG, BrazilUNIFESP, Ctr Clin & Sci Sleep, Dept Neurol, Sao Paulo, SP, BrazilUNIFESP, Dept Internal Med, Sao Paulo, SP, BrazilUNIFESP, Ctr Clin & Sci Sleep, Dept Neurol, Sao Paulo, SP, BrazilUNIFESP, Dept Internal Med, Sao Paulo, SP ...
Abe, Paulo Toshio, Prado, Lucila Bizari Fernandes do [UNIFESP], Vitorino, Débora Fernandes de Melo [UNIFESP], Guimarães, Laiz Helena de Castro Toledo [UNIFESP], Prado, Gilmar Fernandes do [UNIFESP]   +4 more
core  

How Are Australian Local Governments Responding to the Homelessness Crisis? Findings From a National Study

Australian Journal of Social Issues, EarlyView.
ABSTRACT Australian local governments are facing intensifying pressures to respond to worsening visible homelessness. This paper presents one of the first national studies on how local governments are responding to these pressures, and the first since the onset of the post‐pandemic housing crisis.
Andrew Clarke, Joelle Moore, Fatemeh Aminpour, Katya Eagles   +3 more
wiley   +1 more source