Results 171 to 180 of about 47,163 (209)

Antiprotozoal Activity of Highly Substituted Pyrazole and Pyrimidine Derivatives

ChemMedChem, EarlyView.
Based on previously identified antimalarial agents, a series of highly substituted pyrazole and pyrimidines derivatives has been synthesized and tested for antiplasmodial and antileishmanial activity. Selected derivatives show promising antiplasmodial effect with a predicted favorable pharmacokinetic profile.
Matteo Lusardi, Nicoletta Basilico, Erika Iervasi, Chiara Brullo, Silvia Parapini, Marco Ponassi, Camillo Rosano, Andrea Spallarossa   +7 more
wiley   +1 more source

Ferroptosis as a potential molecular mechanism of bipolar disorder. [PDF]

Transl Psychiatry
Yehia A, Melhuish Beaupre LM, Ho MC, Biernnacka JM, Frye MA, Abulseoud OA.   +5 more
europepmc   +1 more source

Integrating Artificial Intelligence and Smartphone Technology to Enhance Personalized Assessment and Treatment for Eating Disorders

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Smartphone technology presents a promising path toward expanding access to evidence‐based eating disorder assessment and treatment. Despite rapid technological advances, research has yet to harness these systems in ways that make personalized digital health care a clinical reality.
Jake Linardon, John Torous
wiley   +1 more source

Peer Review in the Artificial Intelligence Era: A Call for Developing Responsible Integration Guidelines. [PDF]

Nat Sci Sleep
BaHammam AS.
europepmc   +1 more source

Beyond the Diagnostic Checklist: A Large‐Scale Analysis of Under‐Recognized Weight Loss Behaviors in Individuals With Eating Disorders

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective This study aimed to explore the diverse range of weight loss behaviors that extend beyond traditional diagnostic criteria, highlighting the variability in symptom presentation. Method We text mined free‐text responses from 1675 participants with anorexia nervosa, bulimia nervosa, or binge‐eating disorder in the Genetic Links to ...
Saakshi Kakar, Una Foye, Helena L. Davies, Elisavet Palaiologou, Chelsea M. Malouf, Laura Meldrum, Iona Smith, Gursharan Kalsi, Karina L. Allen, Gerome Breen, Moritz Herle, Christopher Hübel   +11 more
wiley   +1 more source

Weighing in: Clinician and Patient Perspectives on Discussions of Expected Body Weights in Eating Disorder Treatment

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Clinicians often determine an “expected body weight” (EBW) for patients who have lost weight due to an eating disorder (ED). However, there is inconsistent guidance and limited empirical research on when, how, and why to discuss EBWs with patients. This study explores clinician and patient perspectives on discussions of EBWs.
Agatha A. Laboe, Ava Heyrman, Siena Vendlinski, Molly F. Steinhoff, Sophia Kreckler, Caitlyn Ruud, Kate Walsh, Daniel W. Grupe, James J. Li, Katherine Schaumberg   +9 more
wiley   +1 more source

Sleep, Well-Being, and Cognition in Medical Interns on a Float or Overnight Call Schedule.

JAMA Netw Open
Massar SAA, Chua XY, Leong R, Golkashani HA, Pu Z, Ng ASC, Ong JL, Soon CS, Ng NBH, Tan MY, Lin JB, Aw M, Chee MWL.   +12 more
europepmc   +1 more source

Phenotyping patients with chronic obstructive pulmonary disease and heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 900-911, April 2025.
Central illustration. Abbreviations: ACEi, angiotensin‐converting enzyme inhibitor; ARB, angiotensin receptor blocker; ARNi, angiotensin‐receptor‐neprilysin inhibitor; CI, confidence interval; COPD, chronic obstructive pulmonary disease; CRT, cardiac resynchronization therapy; CV, cardiovascular; EF, ejection fraction; eGFR, estimated glomerular ...
Peter Moritz Becher, Felix Lindberg, Lina Benson, Camilla Hage, Ulf Dahlström, Stephan Rosenkranz, Francesco Cosentino, Giuseppe M.C. Rosano, Stefan Blankenberg, Paulus Kirchhof, Frieder Braunschweig, Lars H. Lund, Gianluigi Savarese   +12 more
wiley   +1 more source

Global call to understand intersectionality between heat exposure and perinatal mental health. [PDF]

Matern Health Neonatol Perinatol
Kc A, Kreyenbaum L.
europepmc   +1 more source

Immune Checkpoint Inhibitors and Cardiovascular Adverse Events

ESC Heart Failure, EarlyView.
Abstract In the last years, we assisted to a tremendous increase in therapeutic options for the management of cancers, with immunotherapy at the forefront of this innovation. Immune checkpoint inhibitors (ICIs) have been developed to enhance the activity of the immune system against cancer cells (1) and the number of approvals for ICIs has rapidly ...
Maria Luisa De Perna, Elia Rigamonti, Raffaele Zannoni, Vittoria Espeli, Giorgio Moschovitis   +4 more
wiley   +1 more source