Precision therapies for genetic epilepsies in 2025: Promises and pitfalls
Epilepsia Open, EarlyView.Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang +3 more
wiley +1 more source
Friction Characterization and Mitigation in Large‐Scale 6DOF Multi‐Axial Hybrid Simulation
Earthquake Engineering &Structural Dynamics, EarlyView.ABSTRACT In the last few decades, hybrid simulation has become widely used for understanding the response of structural components and systems under extreme loading conditions. Large‐scale, three‐dimensional (3D), multi‐axial testing facilities with six degrees of freedom (6DOF) are versatile testing systems that can be used for testing a variety of ...
Pedram Mortazavi +7 more
wiley +1 more source
Can we learn to recover? Surgeon wellness in a challenging environment. [PDF]
Can J SurgBall CG, Joseph BA, Harvey EJ.
europepmc +1 more source
Opioid Therapy in Chronic Pain: Assessment of Clinical Outcomes and Relationships With Endocrine Biomarkers. [PDF]
Eur J PainAbou-Kassem D +5 more
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Sodium Oxybate: Practical Considerations and Patient Perspectives. [PDF]
CNS DrugsLavender M, Martin C, Anderson D.
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Lifestyle Medicine, the USDA and the Land-Grant University Cooperative Extension System: A Call to Action at the Intersection of Personal, Public and Planetary Health. [PDF]
Am J Lifestyle MedMauro S, Shelnutt KP, Stout R.
europepmc +1 more source
Development of a Qigong Used for Insomnia Therapy (QUIT) Program for Improving Sleep Quality and Blood Pressure in Chinese Women With Menopause: Pre-Post Pilot Test of Feasibility. [PDF]
Asian Pac Isl Nurs JHuang S, Kim JE, Li WW.
europepmc +1 more source