Results 31 to 40 of about 985,775 (254)

A neuro-cardiac self-regulation therapy to improve autonomic and neural function after SCI: a randomized controlled trial protocol

BMC Neurology, 2021
Background Spinal cord injury (SCI) is associated with autonomic imbalance and significant secondary conditions, including cardiac and brain dysfunction that adversely impact health and wellbeing.
Ashley Craig, Ilaria Pozzato, Mohit Arora, James Middleton, Dianah Rodrigues, Candice McBain, Yvonne Tran, Glen M. Davis, Bamini Gopinath, Annette Kifley, Andrei Krassioukov, Jeffrey Braithwaite, Rebecca Mitchell, Sylvia M. Gustin, Jacob Schoffl, Ian D. Cameron   +15 more
doaj   +1 more source

Sensory gating and gaining in sleep: the balance between the protection of sleep and the safeness of life (a review)

Journal of Sleep Research
Sleep is a brain state characterised by a low vigilance level and diminished consciousness. Reaction to and processing of external stimuli is attenuated in sleep.
Anton M. L. Coenen
semanticscholar   +1 more source

Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins

FEBS Open Bio, EarlyView.
We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó, Eszter Nagy‐Kanta, Soma Varga, Edit Andrea Jáger, Csaba István Pongor, Mária Laki, András József Laki, Zoltán Gáspári   +7 more
wiley   +1 more source

Sleep quality and the integrity of ascending reticular activating system – A multimodal MRI study

Heliyon
Sleep is crucial for maintaining brain homeostasis and individuals with insufficient sleep are prone to more pronounced brain atrophy as compared to sufficiently sleeping peers.
Viktória Kokošová, Lubomír Vojtíšek, Marek Baláž, Silvia Mangia, Shalom Michaeli, Pavel Filip   +5 more
doaj   +1 more source

Aerobic exercise program with or without motor complexity as an add-on to the pharmacological treatment of depression – study protocol for a randomized controlled trial

Trials, 2018
Background Patients with major depression disorder presents increased rates of cognitive decline, reduced hippocampal volume, poor sleep quality, hypertension, obesity, suicidal ideation and behavior, and decreased functionality.
Lucas Melo Neves, Carla Silva-Batista, Raquel Marquesini, Telma Fátima da Cunha, Elisa Dimateo, Luciana Nascimento, Acácio Moreira-Neto, Angelo Corrêa de Lima Miliatto, Sheila das Chagas Mendes, Flavia Saad, Jamile Sanches Codogno, Renato Hoffmann Nunes, Raphael Mendes Ritti-Dias, Valeria Juday, Beny Lafer, Carlos Ugrinowitsch   +15 more
doaj   +1 more source

The Development and Evaluation of a Text Message Program to Prevent Perceived Insufficient Milk Among First-Time Mothers: Retrospective Analysis of a Randomized Controlled Trial

JMIR mHealth and uHealth, 2020
BackgroundSeveral recent trials have examined the feasibility and efficacy of automated SMS text messaging to provide remote breastfeeding support to mothers, but these texting systems vary in terms of design features and outcomes examined ...
Demirci, Jill R, Suffoletto, Brian, Doman, Jack, Glasser, Melissa, Chang, Judy C, Sereika, Susan M, Bogen, Debra L   +6 more
doaj   +1 more source

Genetic Modifiers of Parkinson's Disease: A Case–Control Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the associations of LRRK2 p.G2019S, GBA1 p.N409S, polygenic risk scores (PRS), and APOE E4 on PD penetrance, risk, and symptoms. Methods We conducted a US‐based observational case–control study using data from the 23andMe Inc. and Fox Insight Genetic Substudy (FIGS) databases.
Matthew J. Kmiecik, Michael V. Holmes, Pierre Fontanillas, Giulietta M. Riboldi, Ruth B. Schneider, Jingchunzi Shi, Anna Guan, Susana Tat, Steven Micheletti, Keaton Stagaman, Josh Gottesman, David A. Hinds, Joyce Y. Tung, 23andMe Research Team, Stella Aslibekyan, Lucy Norcliffe‐Kaufmann   +15 more
wiley   +1 more source

Characteristics of Cerebral Palsy in the Midwestern US

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebral palsy (CP) is the most common lifelong motor disability worldwide. Yet, data is limited on how CP manifests in the US. Our objective was to characterize and determine factors affecting functional outcomes in a large population of young people with CP in the Midwestern US.
Susie Kim, Kelsey Steffen, Lauren Gottschalk‐Henneberry, Jennifer Miros, Amy Robichaux‐Viehoever, Karen Taca, Bhooma R. Aravamuthan   +6 more
wiley   +1 more source

Autism and mild epilepsy associated with a de novo missense pathogenic variant in the GTPase effector domain of DNM1

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023
Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei, Elena Parrini, Claudia Bianchini, Maria Luisa Ricci, Renzo Guerrini   +4 more
wiley   +1 more source

High-Stress Shifts Among Orthopaedic Trainees Alter Cognitive Abilities and Surgical Performance

Foot & Ankle Orthopaedics
Category: Other; Trauma Introduction/Purpose: The effect of sleep deprivation and environmental stresses for orthopaedic trainees can manifest as physical and mental impairment in addition to worsening psychomotor performances. Lack of sleep and rest may
Kempland C. Walley MD, Michal Jandzinski MD, Ross Michaels MD, Jack Eichman BS, Mark Hake MD, Jaimo Ahn MD PhD, James Holmes MD   +6 more
doaj   +1 more source